Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7932.002 | 1.0236 | 1.0526 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7932.002 | 1.0348 | 1.0776 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7932.002 | 1.0158 | 1.0351 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7932.002 | 0.9170 | 0.8163 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7932.002 | 0.8072 | 0.5761 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7932.002 | 0.7095 | 0.3653 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7932.002 | 0.7330 | 0.4158 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7932.002 | 0.8076 | 0.5769 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7932.002 | 0.7688 | 0.4929 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9958.002 | 1.0077 | 1.0303 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9958.002 | 1.0022 | 1.0084 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9958.002 | 0.9860 | 0.9458 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9958.002 | 0.9200 | 0.6990 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9958.002 | 0.8398 | 0.4213 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9958.002 | 0.7943 | 0.2746 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9958.002 | 0.8182 | 0.3510 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9958.002 | 0.8424 | 0.4301 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9958.002 | 0.7728 | 0.2081 | 0.5113 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9972.002 | 1.0462 | 1.0920 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9972.002 | 1.0215 | 1.0427 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9972.002 | 0.9944 | 0.9888 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9972.002 | 0.7452 | 0.4927 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9972.002 | 0.6584 | 0.3198 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9972.002 | 0.6207 | 0.2445 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9972.002 | 0.5890 | 0.1814 | 1.0054 |