Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13078.002 | 0.9749 | 0.9225 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13078.002 | 0.9511 | 0.8503 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 13078.002 | 0.6181 | -0.0529 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 13078.002 | 0.5597 | -0.1883 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 13078.002 | 0.5346 | -0.2441 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 13078.002 | 0.5535 | -0.2021 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 13078.002 | 0.5961 | -0.1047 | 0.6437 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9933.002 | 0.9586 | 0.8130 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9933.002 | 1.0907 | 1.4471 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9933.002 | 1.0261 | 1.1234 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9933.002 | 1.0018 | 1.0084 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9933.002 | 0.7713 | 0.0943 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9933.002 | 0.4403 | -0.7024 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9933.002 | 0.4179 | -0.7364 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9933.002 | 0.4576 | -0.6746 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9933.002 | 0.5738 | -0.4496 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9953.002 | 0.9938 | 0.9702 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9953.002 | 1.1384 | 1.7354 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9953.002 | 1.0031 | 1.0151 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9953.002 | 1.0023 | 1.0110 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9953.002 | 0.9696 | 0.8562 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9953.002 | 0.8520 | 0.3584 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9953.002 | 0.7859 | 0.1179 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9953.002 | 0.9160 | 0.6180 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9953.002 | 0.8067 | 0.1904 | 0.4141 |