Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9913.002 | 0.6745 | 0.1133 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9913.002 | 0.6388 | 0.0268 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9913.002 | 0.6380 | 0.0250 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9913.002 | 0.7239 | 0.2367 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9913.002 | 0.7594 | 0.3280 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10150.002 | 1.0418 | 1.2121 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10150.002 | 1.1114 | 1.5938 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10150.002 | 0.9640 | 0.8275 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10150.002 | 0.8412 | 0.3068 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10150.002 | 0.6568 | -0.2891 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10150.002 | 0.6911 | -0.1942 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10150.002 | 0.6671 | -0.2613 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10150.002 | 0.7494 | -0.0164 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10150.002 | 0.7456 | -0.0289 | 0.4064 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10267.002 | 1.0526 | 1.2686 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10267.002 | 1.2520 | 2.4746 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10267.002 | 0.9861 | 0.9324 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10267.002 | 0.9571 | 0.7958 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10267.002 | 0.6412 | -0.3291 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10267.002 | 0.6746 | -0.2400 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10267.002 | 0.5930 | -0.4464 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10267.002 | 0.6700 | -0.2526 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10267.002 | 0.7187 | -0.1119 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13078.002 | 1.0008 | 1.0024 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13078.002 | 1.0611 | 1.1931 | 0.6437 |