Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13570.174 | 0.8875 | 0.5895 | 0.5197 | |
| SUM52PE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13570.174 | 0.8730 | 0.5399 | 0.5197 | |
| SUM52PE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13570.174 | 0.8710 | 0.5332 | 0.5197 | |
| SUM52PE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13570.174 | 0.9413 | 0.7803 | 0.5197 | |
| SUM52PE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13570.174 | 0.9261 | 0.7255 | 0.5197 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12720.174 | 0.9678 | 0.9335 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12720.174 | 0.9578 | 0.9129 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12720.174 | 0.9311 | 0.8579 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12720.174 | 0.9831 | 0.9650 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12720.174 | 0.7131 | 0.4108 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12720.174 | 0.5079 | -0.0062 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12720.174 | 0.6748 | 0.3325 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12720.174 | 0.8171 | 0.6235 | 0.9688 | |
| T47D | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12720.174 | 0.7676 | 0.5221 | 0.9688 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13070.174 | 0.9966 | 0.9914 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13070.174 | 0.9878 | 0.9696 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13070.174 | 0.9672 | 0.9183 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13070.174 | 0.9904 | 0.9760 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13070.174 | 0.7735 | 0.4504 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13070.174 | 0.6343 | 0.1317 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13070.174 | 0.7925 | 0.4950 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13070.174 | 0.8296 | 0.5831 | 0.7993 | |
| T47DKBLUC | Unknown | Unknown | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13070.174 | 0.8018 | 0.5170 | 0.7993 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13078.174 | 0.9578 | 0.8663 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13078.174 | 0.9829 | 0.9455 | 0.6238 |