Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13587.176 | 0.9719 | 0.9240 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13587.176 | 0.9756 | 0.9341 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13587.176 | 1.0233 | 1.0636 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13587.176 | 0.9949 | 0.9862 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13587.176 | 0.9578 | 0.8864 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13587.176 | 0.9531 | 0.8737 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13587.176 | 0.9434 | 0.8478 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13587.176 | 0.9967 | 0.9911 | 0.7367 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13587.176 | 0.9570 | 0.8841 | 0.7367 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12964.176 | 0.9512 | 0.8968 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12964.176 | 0.9297 | 0.8515 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12964.176 | 0.9737 | 0.9443 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12964.176 | 0.9578 | 0.9108 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12964.176 | 0.9651 | 0.9263 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12964.176 | 0.9282 | 0.8483 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12964.176 | 0.9243 | 0.8400 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12964.176 | 0.9296 | 0.8512 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12964.176 | 0.8774 | 0.7414 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13562.176 | 1.0098 | 1.0238 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13562.176 | 0.9810 | 0.9539 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13562.176 | 1.0193 | 1.0470 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13562.176 | 1.0491 | 1.1203 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13562.176 | 0.9430 | 0.8621 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13562.176 | 0.9599 | 0.9027 | 0.8217 | |
| MDA-MB-453 | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13562.176 | 0.9180 | 0.8023 | 0.8217 |