Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 7540.078 | 1.0293 | 1.0615 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 7540.078 | 1.1605 | 1.3383 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 7540.078 | 0.8298 | 0.6442 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 7540.078 | 1.0417 | 1.0876 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 7540.078 | 1.0788 | 1.1658 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 7540.078 | 0.8794 | 0.7474 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 7540.078 | 0.5967 | 0.1629 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 7540.078 | 0.2441 | -0.5452 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 7540.078 | 0.0571 | -0.9011 | 0.9523 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 9889.034 | 0.9824 | 0.9743 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 9889.034 | 1.0055 | 1.0080 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 9889.034 | 0.9716 | 0.9586 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 9889.034 | 1.0480 | 1.0694 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 9889.034 | 0.9996 | 0.9995 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 9889.034 | 0.8114 | 0.7178 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 9889.034 | 0.3237 | -0.1198 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 9889.034 | 0.2235 | -0.3279 | 1.3742 | |
| SUM52PE | HR+ | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 9889.034 | 0.0964 | -0.6355 | 1.3742 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 9897.034 | 1.0279 | 1.1449 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 9897.034 | 1.0582 | 1.3088 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 9897.034 | 1.0074 | 1.0379 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 9897.034 | 0.9818 | 0.9089 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 9897.034 | 1.0407 | 1.2131 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 9897.034 | 0.8571 | 0.3523 | 0.3940 | |
| T47D | HR+ | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 9897.034 | 0.6404 | -0.3547 | 0.3940 |