Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	50	uM	9047.017	0.2223	-0.6633	0.8440
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	250	uM	9047.017	0.0074	-0.9940	0.8440
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.00064	uM	10002.021	1.0072	1.0202	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.0032	uM	10002.021	0.9698	0.9164	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.016	uM	10002.021	0.9866	0.9628	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.08	uM	10002.021	0.9550	0.8760	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.4	uM	10002.021	0.9876	0.9656	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	2	uM	10002.021	0.8751	0.6615	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	10	uM	10002.021	0.3443	-0.5456	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	50	uM	10002.021	0.1122	-0.9044	0.7195
184A1	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	250	uM	10002.021	0.0465	-0.9719	0.7195
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.00128	uM	9095.049	1.0023	1.0040	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.0064	uM	9095.049	1.0167	1.0297	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.032	uM	9095.049	1.0277	1.0494	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.16	uM	9095.049	0.9677	0.9422	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	0.8	uM	9095.049	1.0140	1.0250	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	4	uM	9095.049	0.9866	0.9761	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	20	uM	9095.049	1.0173	1.0309	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	100	uM	9095.049	0.9874	0.9775	1.1202
184B5	NM	Basal	Cisplatin	DNA cross-linker	DNA cross-linker	500	uM	9095.049	0.8423	0.7160	1.1202
600MPE	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.00064	uM	9118.017	1.0513	1.0985	1.0401
600MPE	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.0032	uM	9118.017	0.9569	0.9171	1.0401
600MPE	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.016	uM	9118.017	1.0299	1.0574	1.0401
600MPE	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.08	uM	9118.017	1.0049	1.0095	1.0401
600MPE	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.4	uM	9118.017	1.0219	1.0421	1.0401

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)