Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.00017 | uM | 13070.177 | 0.8749 | 0.7252 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.000851 | uM | 13070.177 | 0.8585 | 0.6894 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.00426 | uM | 13070.177 | 0.8451 | 0.6603 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.0213 | uM | 13070.177 | 0.7364 | 0.4257 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.106 | uM | 13070.177 | 0.9676 | 0.9285 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 0.532 | uM | 13070.177 | 0.9570 | 0.9052 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 2.66 | uM | 13070.177 | 0.8511 | 0.6734 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 13.3 | uM | 13070.177 | 0.6258 | 0.1908 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | Chloroquine | 66.5 | uM | 13070.177 | 0.0002 | -0.9998 | 0.9040 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.00017 | uM | 12677.177 | 1.0237 | 1.0451 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.000851 | uM | 12677.177 | 0.9664 | 0.9360 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.00426 | uM | 12677.177 | 0.9818 | 0.9654 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.0213 | uM | 12677.177 | 0.7127 | 0.4492 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.106 | uM | 12677.177 | 0.9214 | 0.8503 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 0.532 | uM | 12677.177 | 0.9482 | 0.9013 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 2.66 | uM | 12677.177 | 0.9832 | 0.9680 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 13.3 | uM | 12677.177 | 0.7717 | 0.5630 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | Chloroquine | 66.5 | uM | 12677.177 | 0.0752 | -0.8292 | 1.0515 | |||
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9047.017 | 1.1689 | 1.4062 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9047.017 | 1.0589 | 1.1404 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9047.017 | 0.9629 | 0.9124 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9047.017 | 1.0460 | 1.1094 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9047.017 | 0.9697 | 0.9284 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9047.017 | 0.9143 | 0.7986 | 0.8440 | |
| 184A1 | NM | Basal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9047.017 | 0.1797 | -0.7383 | 0.8440 |