Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7837.042 | 0.5906 | 0.4649 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7837.042 | 0.7698 | 0.7134 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7837.042 | 0.9842 | 0.9812 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7837.042 | 1.0055 | 1.0065 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7837.042 | 0.9271 | 0.9124 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7837.042 | 0.8736 | 0.8465 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7837.042 | 0.8064 | 0.7611 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7837.042 | 0.8090 | 0.7645 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7837.042 | 0.6339 | 0.5276 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9386.026 | 0.9910 | 0.9884 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9386.026 | 1.0587 | 1.0745 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9386.026 | 0.9120 | 0.8851 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9386.026 | 1.0087 | 1.0111 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9386.026 | 0.9950 | 0.9935 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9386.026 | 0.8788 | 0.8409 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9386.026 | 0.8258 | 0.7688 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 9386.026 | 0.7826 | 0.7088 | 1.5583 | |
| HCC1954 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 9386.026 | 0.7485 | 0.6607 | 1.5583 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7840.018 | 1.0035 | 1.0170 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7840.018 | 1.0110 | 1.0539 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7840.018 | 1.0121 | 1.0594 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7840.018 | 0.9379 | 0.7112 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7840.018 | 0.9901 | 0.9522 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7840.018 | 0.9891 | 0.9476 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7840.018 | 0.9666 | 0.8413 | 0.4113 |