Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9045.075 | 1.0918 | 1.2251 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9045.075 | 0.1276 | -0.8358 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9933.021 | 0.9360 | 0.6377 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9933.021 | 1.1089 | 1.7332 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9933.021 | 1.0082 | 1.0500 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9933.021 | 1.0123 | 1.0751 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9933.021 | 1.0563 | 1.3600 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9933.021 | 0.9765 | 0.8615 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9933.021 | 1.0370 | 1.2318 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9933.021 | 1.1357 | 1.9374 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9933.021 | 0.2827 | -0.9560 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9953.011 | 1.0058 | 1.0249 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9953.011 | 1.0930 | 1.4169 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9953.011 | 0.9241 | 0.6907 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9953.011 | 0.9908 | 0.9610 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9953.011 | 1.0269 | 1.1162 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9953.011 | 1.0935 | 1.4194 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9953.011 | 0.9887 | 0.9521 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9953.011 | 1.0037 | 1.0158 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9953.011 | 0.1373 | -0.9708 | 0.4697 | |
| ZR-75-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7931.011 | 0.9901 | 0.9848 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7931.011 | 1.0151 | 1.0232 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7931.011 | 0.9779 | 0.9658 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7931.011 | 1.0073 | 1.0112 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7931.011 | 0.9638 | 0.9441 | 1.2993 |