Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7493.074 | 0.2573 | -0.3827 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7493.074 | 0.0477 | -0.8565 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7493.074 | 0.0477 | -0.8565 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7493.074 | 0.0360 | -0.8876 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7493.074 | 0.0360 | -0.8876 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14755.203 | 0.9200 | 0.9198 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14755.203 | 0.9200 | 0.9198 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14755.203 | 0.9252 | 0.9251 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14755.203 | 0.9252 | 0.9251 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14755.203 | 0.9425 | 0.9427 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14755.203 | 0.9425 | 0.9427 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14755.203 | 0.6085 | 0.5672 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14755.203 | 0.6085 | 0.5672 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14755.203 | 0.3922 | 0.2633 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14755.203 | 0.3922 | 0.2633 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14755.203 | 0.3245 | 0.1511 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14755.203 | 0.3245 | 0.1511 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14755.203 | 0.2247 | -0.0390 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14755.203 | 0.2247 | -0.0390 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14755.203 | 0.1112 | -0.3195 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14755.203 | 0.1112 | -0.3195 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14755.203 | 0.0761 | -0.4352 | 2.0371 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14755.203 | 0.0761 | -0.4352 | 2.0371 | |
| MDA-MB-134-VI | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7494.074 | 0.9939 | 0.9821 | 0.6767 | |
| MDA-MB-134-VI | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7494.074 | 0.9939 | 0.9821 | 0.6767 |