Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0107	uM	7483.074	0.9269	0.9540	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0107	uM	7483.074	0.9269	0.9540	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0533	uM	7483.074	1.1005	1.0596	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0533	uM	7483.074	1.1005	1.0596	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.267	uM	7483.074	0.8607	0.9101	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.267	uM	7483.074	0.8607	0.9101	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	1.33	uM	7483.074	0.4046	0.5154	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	1.33	uM	7483.074	0.4046	0.5154	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	6.67	uM	7483.074	0.2554	0.3160	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	6.67	uM	7483.074	0.2554	0.3160	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	33.3	uM	7483.074	0.0308	-0.3120	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	33.3	uM	7483.074	0.0308	-0.3120	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	167	uM	7483.074	0.0096	-0.5185	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	167	uM	7483.074	0.0096	-0.5185	3.2613
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.000427	uM	7484.074	1.1098	1.0813	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.000427	uM	7484.074	1.1098	1.0813	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.00213	uM	7484.074	1.0316	1.0240	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.00213	uM	7484.074	1.0316	1.0240	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0107	uM	7484.074	1.0208	1.0158	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0107	uM	7484.074	1.0208	1.0158	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0533	uM	7484.074	0.9573	0.9669	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.0533	uM	7484.074	0.9573	0.9669	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.267	uM	7484.074	0.8790	0.9037	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	0.267	uM	7484.074	0.8790	0.9037	2.6137
MCF 10A	NM	Basal B	Bortezomib	Proteasome	Proteasome	1.33	uM	7484.074	0.6012	0.6462	2.6137

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)