Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7515.066 | 0.9346 | 0.8913 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7515.066 | 0.7681 | 0.6081 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7515.066 | 0.8418 | 0.7347 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7515.066 | 0.8892 | 0.8149 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7515.066 | 0.8888 | 0.8144 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7515.066 | 0.7664 | 0.6052 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7515.066 | 0.9134 | 0.8558 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7515.066 | 0.8051 | 0.6719 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7515.066 | 0.6593 | 0.4175 | 1.2099 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7516.066 | 0.9969 | 0.9948 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7516.066 | 0.9692 | 0.9483 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7516.066 | 0.9737 | 0.9558 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7516.066 | 1.0262 | 1.0437 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7516.066 | 0.9797 | 0.9660 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7516.066 | 0.9778 | 0.9627 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7516.066 | 0.9595 | 0.9319 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7516.066 | 0.9563 | 0.9266 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7516.066 | 0.9972 | 0.9953 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7517.066 | 0.9747 | 0.9616 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7517.066 | 0.9897 | 0.9844 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7517.066 | 1.0125 | 1.0189 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7517.066 | 1.0145 | 1.0219 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7517.066 | 1.0384 | 1.0578 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7517.066 | 0.9753 | 0.9625 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7517.066 | 1.0217 | 1.0327 | 1.3218 |