Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9210.024 | 0.6135 | 0.1404 | 0.8697 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7807.016 | 0.9602 | 0.9626 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7807.016 | 0.9198 | 0.9238 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7807.016 | 0.9302 | 0.9338 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7807.016 | 0.9186 | 0.9226 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7807.016 | 0.9277 | 0.9315 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.267 | uM | 7807.016 | 0.9271 | 0.9309 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 1.33 | uM | 7807.016 | 0.9377 | 0.9411 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 6.67 | uM | 7807.016 | 0.8467 | 0.8511 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 33.3 | uM | 7807.016 | 0.2186 | -0.0134 | 2.1516 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7808.016 | 1.0455 | 1.0401 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7808.016 | 1.0561 | 1.0493 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7808.016 | 1.0334 | 1.0295 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7808.016 | 1.1547 | 1.1327 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7808.016 | 1.0350 | 1.0310 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.267 | uM | 7808.016 | 1.0043 | 1.0038 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 1.33 | uM | 7808.016 | 1.0688 | 1.0603 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 6.67 | uM | 7808.016 | 0.9635 | 0.9670 | 2.2401 | |
| HBL-100 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 33.3 | uM | 7808.016 | 0.3457 | 0.2448 | 2.2401 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7809.016 | 0.8798 | 0.8517 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7809.016 | 0.9722 | 0.9663 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7809.016 | 0.8874 | 0.8613 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7809.016 | 1.0036 | 1.0043 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7809.016 | 0.9478 | 0.9365 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7809.016 | 0.8950 | 0.8709 | 1.6622 |