Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with nine kinase inhibitors - Dataset (ID:20266)

Proteins Studied

  • 25 Proteins
LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
201398 4EBP1 (pT46) 201398 Q13541 pT46
201397 4EBP1 (pT37) 201397 Q13541 pT37
201396 4EBP1 (pT37; pT46) 201396 Q13541 pT37; pT46
201392 Survivin 201392 O15392
Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin
201391 p57Kip2 (pT310) 201391 P49918 pT310
201390 Akt-1 (pS473) 201390 P31749 pS473
201389 p57Kip2 201389 P49918
Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57
201388 p27Kip1 (pS10) 201388 P46527 pS10
201387 CDK2 (pY15) 201387 P24941 pY15
201386 CDK1 (pY15) 201386 P06493 pY15
201385 FoxM1 201385 Q08050
Forkhead box protein M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/fork-head homolog 11; M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells
201384 Cyclin-B1 201384 P14635
G2/mitotic-specific cyclin-B1
201381 S6K-alpha-1 (pS380) 201381 Q15418 pS380
201364 Cyclin-A2 201364 P20248
Cyclin-A
201363 Cyclin-A1 201363 P78396
201362 p27Kip1 (pT187) 201362 P46527 pT187
201350 FOXO3a 201350 O43524
Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
201344 p27Kip1 201344 P46527
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27
201338 ERK-2 (pT185) 201338 P28482 pT185
201337 ERK-1 (pT202) 201337 P27361 pT202
201304 ERK-2 (pT185; pY187) 201304 P28482 pT185; pY187
201303 ERK-1 (pT202; pY204) 201303 P27361 pT202; pY204
201299 S6 (pS240; pS244) 201299 P62753 pS240; pS244
201297 Rb (pS807; pS811) 201297 P06400 pS807; pS811
201295 p21 201295 P38936
Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6
  • 25 Proteins