Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 5000.00 | 2099.14 | 11123.00 | 11036.50 | 1.0078 | 1.0065 |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 10462.00 | 11036.50 | 0.9480 | 0.9558 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 10896.00 | 11036.50 | 0.9873 | 0.9893 |
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 7435.00 | 11036.50 | 0.6737 | 0.6958 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11484.00 | 11036.50 | 1.0405 | 1.0335 | |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 241.00 | 262.75 | 0.9172 | 0.9324 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 156.25 | 46.09 | 217.00 | 262.75 | 0.8259 | 0.8533 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 156.25 | 46.09 | 97.00 | 262.75 | 0.3692 | 0.3449 |
MCF 10A | Linsitinib | 10 | uM | 9 | 156.25 | 46.09 | 69.00 | 262.75 | 0.2626 | 0.1743 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 156.25 | 46.09 | 462.00 | 262.75 | 1.7583 | 1.5040 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 156.25 | 46.09 | 49.00 | 262.75 | 0.1865 | 0.0247 |
MCF 10A | Erlotinib | 1 | uM | 9 | 156.25 | 46.09 | 60.00 | 262.75 | 0.2284 | 0.1107 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 156.25 | 46.09 | 117.00 | 262.75 | 0.4453 | 0.4491 |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 373.00 | 262.75 | 1.4196 | 1.2995 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 156.25 | 46.09 | 155.00 | 262.75 | 0.5899 | 0.6209 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 156.25 | 46.09 | 316.00 | 262.75 | 1.2027 | 1.1525 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 156.25 | 46.09 | 508.00 | 262.75 | 1.9334 | 1.6005 |
MCF 10A | 17-AAG | 0.0001 | uM | 9 | 156.25 | 46.09 | 199.00 | 262.75 | 0.7574 | 0.7905 |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 248.00 | 262.75 | 0.9439 | 0.9545 | |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 156.25 | 46.09 | 134.00 | 262.75 | 0.5100 | 0.5296 |
MCF 10A | Erlotinib | 10 | uM | 9 | 156.25 | 46.09 | 70.00 | 262.75 | 0.2664 | 0.1811 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 156.25 | 46.09 | 198.00 | 262.75 | 0.7536 | 0.7869 |
MCF 10A | Lapatinib | 10 | uM | 9 | 156.25 | 46.09 | 23.00 | 262.75 | 0.0875 | -0.2418 |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 331.00 | 262.75 | 1.2598 | 1.1926 | |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 245.00 | 262.75 | 0.9325 | 0.9451 |