Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | PLX-4720 | 10 | uM | 6 | 1250.00 | 531.21 | 6620.00 | 9900.50 | 0.6687 | 0.8181 |
MCF 10A | Nilotinib | 19.9526 | uM | 6 | 1250.00 | 531.21 | 1170.00 | 9900.50 | 0.1182 | 0.2058 |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 10275.00 | 9900.50 | 1.0378 | 1.0177 | |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 6 | 1250.00 | 531.21 | 1838.00 | 9900.50 | 0.1857 | 0.3420 |
MCF 10A | Etoposide | 0.0033113 | uM | 6 | 1250.00 | 531.21 | 10311.00 | 9900.50 | 1.0415 | 1.0193 |
MCF 10A | PLX-4720 | 19.9526 | uM | 6 | 1250.00 | 531.21 | 3680.00 | 9900.50 | 0.3717 | 0.5819 |
MCF 10A | Etoposide | 3.1623 | uM | 6 | 1250.00 | 531.21 | 620.00 | 9900.50 | 0.0626 | 0.0373 |
MCF 10A | NVP-TAE684 | 10 | uM | 6 | 1250.00 | 531.21 | 481.00 | 9900.50 | 0.0486 | -0.0233 |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 8809.50 | 9900.50 | 0.8898 | 0.9454 | |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 10008.00 | 9900.50 | 1.0109 | 1.0051 | |
MCF 10A | 0 | uM | 6 | 2500.00 | 1235.29 | 10754.00 | 10391.25 | 1.0349 | 1.0225 | |
MCF 10A | 0 | uM | 6 | 2500.00 | 1235.29 | 10134.00 | 10391.25 | 0.9752 | 0.9838 | |
MCF 10A | Etoposide | 10 | uM | 6 | 2500.00 | 1235.29 | 1226.00 | 10391.25 | 0.1180 | -0.0025 |
MCF 10A | 0 | uM | 6 | 2500.00 | 1235.29 | 9846.00 | 10391.25 | 0.9475 | 0.9652 | |
MCF 10A | 0 | uM | 6 | 2500.00 | 1235.29 | 10185.00 | 10391.25 | 0.9802 | 0.9870 | |
MCF 10A | Etoposide | 1 | uM | 6 | 2500.00 | 1235.29 | 1699.00 | 10391.25 | 0.1635 | 0.1093 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 6 | 2500.00 | 1235.29 | 8511.00 | 10391.25 | 0.8191 | 0.8742 |
MCF 10A | Nilotinib | 0.031623 | uM | 6 | 2500.00 | 1235.29 | 11181.00 | 10391.25 | 1.0760 | 1.0483 |
MCF 10A | Nilotinib | 3.1623 | uM | 6 | 2500.00 | 1235.29 | 10683.00 | 10391.25 | 1.0281 | 1.0181 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 6 | 2500.00 | 1235.29 | 10557.00 | 10391.25 | 1.0160 | 1.0103 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 6 | 2500.00 | 1235.29 | 10502.00 | 10391.25 | 1.0107 | 1.0069 |
MCF 10A | 0 | uM | 6 | 2500.00 | 1235.29 | 10565.00 | 10391.25 | 1.0167 | 1.0108 | |
MCF 10A | Etoposide | 0.1 | uM | 6 | 2500.00 | 1235.29 | 8098.00 | 10391.25 | 0.7793 | 0.8441 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 6 | 2500.00 | 1235.29 | 10813.00 | 10391.25 | 1.0406 | 1.0261 |
MCF 10A | Nilotinib | 0.0033113 | uM | 6 | 2500.00 | 1235.29 | 10722.00 | 10391.25 | 1.0318 | 1.0205 |