LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 XL147
3.33
uM
LJP5
 1.0695 0.0218 1.0720 0.0231
MCF7 XL147
10
uM
LJP5
 0.6807 0.0308 0.6289 0.0426
MCF7 Y39983
0.04
uM
LJP6
 1.0521 0.0235 1.0579 0.0284
MCF7 Y39983
0.12
uM
LJP6
 1.0357 0.0212 1.0403 0.0248
MCF7 Y39983
0.37
uM
LJP6
 1.0010 0.0201 1.0016 0.0223
MCF7 Y39983
1.11
uM
LJP6
 0.9180 0.0537 0.9052 0.0655
MCF7 Y39983
3.33
uM
LJP6
 0.6968 0.0777 0.6296 0.1095
MCF7 Y39983
10
uM
LJP6
 0.1752 0.0187 -0.2435 0.0758
MCF7 Nintedanib
0.04
uM
LJP6
 0.9996 0.0214 0.9992 0.0250
MCF7 Nintedanib
0.12
uM
LJP6
 0.9049 0.0368 0.8916 0.0420
MCF7 Nintedanib
0.37
uM
LJP6
 0.7886 0.0534 0.7483 0.0718
MCF7 Nintedanib
1.11
uM
LJP6
 0.6327 0.0555 0.5447 0.0874
MCF7 Nintedanib
3.33
uM
LJP6
 0.4828 0.0695 0.3258 0.1158
MCF7 Nintedanib
10
uM
LJP6
 0.3145 0.0549 0.0380 0.1269
MCF7 Foretinib
0.04
uM
LJP5
 1.0137 0.0130 1.0137 0.0143
MCF7 Foretinib
0.12
uM
LJP5
 0.5864 0.0747 0.4947 0.1167
MCF7 Foretinib
0.37
uM
LJP5
 0.3433 0.0125 0.1336 0.0108
MCF7 Foretinib
1.11
uM
LJP5
 0.2973 0.0298 0.0492 0.0224
MCF7 Foretinib
3.33
uM
LJP5
 0.2740 0.0211 0.0050 0.0090
MCF7 Foretinib
10
uM
LJP5
 0.1689 0.0191 -0.2249 0.0144
MCF7 AZD 5438
0.04
uM
LJP6
 0.8300 0.0546 0.7976 0.0726
MCF7 AZD 5438
0.12
uM
LJP6
 0.5112 0.0307 0.3733 0.0639
MCF7 AZD 5438
0.37
uM
LJP6
 0.3043 0.0140 0.0311 0.0265
MCF7 AZD 5438
1.11
uM
LJP6
 0.2365 0.0303 -0.1060 0.0652
MCF7 AZD 5438
3.33
uM
LJP6
 0.1616 0.0192 -0.2766 0.0206