LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
1.11
uM
LJP5
72
hr
513 10885 10362 1.0506 1.0228
MCF 10A Nilotinib
3.33
uM
LJP5
72
hr
513 10452 10362 1.0091 1.0037
MCF 10A Nilotinib
10
uM
LJP5
72
hr
513 3764 10362 0.3636 0.5801
MCF 10A JNK-9L
0.04
uM
LJP6
72
hr
513 9018 10473 0.8612 0.9324
MCF 10A JNK-9L
0.12
uM
LJP6
72
hr
513 7616 10473 0.7272 0.8588
MCF 10A JNK-9L
0.37
uM
LJP6
72
hr
513 3138 10473 0.2996 0.5158
MCF 10A JNK-9L
1.11
uM
LJP6
72
hr
513 783 10473 0.0748 0.1017
MCF 10A JNK-9L
3.33
uM
LJP6
72
hr
513 592 10473 0.0566 0.0325
MCF 10A JNK-9L
10
uM
LJP6
72
hr
513 515 10473 0.0492 0.0005
MCF 10A PD0325901
0.04
uM
LJP5
72
hr
513 1058 10362 0.1020 0.1791
MCF 10A PD0325901
0.04
uM
LJP6
72
hr
513 1025 10473 0.0979 0.1696
MCF 10A PD0325901
0.12
uM
LJP5
72
hr
513 842 10362 0.0812 0.1206
MCF 10A PD0325901
0.12
uM
LJP6
72
hr
513 687 10473 0.0656 0.0682
MCF 10A PD0325901
0.37
uM
LJP5
72
hr
513 801 10362 0.0772 0.1051
MCF 10A PD0325901
0.37
uM
LJP6
72
hr
513 675 10473 0.0644 0.0647
MCF 10A PD0325901
1.11
uM
LJP5
72
hr
513 721 10362 0.0696 0.0811
MCF 10A PD0325901
1.11
uM
LJP6
72
hr
513 535 10473 0.0511 0.0096
MCF 10A PD0325901
3.33
uM
LJP5
72
hr
513 579 10362 0.0559 0.0268
MCF 10A PD0325901
3.33
uM
LJP6
72
hr
513 493 10473 0.0471 -0.0101
MCF 10A PD0325901
10
uM
LJP5
72
hr
513 575 10362 0.0555 0.0255
MCF 10A PD0325901
10
uM
LJP6
72
hr
513 398 10473 0.0380 -0.0571
MCF 10A Geldanamycin
0.04
uM
LJP5
72
hr
513 607 10362 0.0586 0.0393
MCF 10A Geldanamycin
0.04
uM
LJP6
72
hr
513 641 10473 0.0612 0.0518
MCF 10A Geldanamycin
0.12
uM
LJP5
72
hr
513 528 10362 0.0510 0.0052
MCF 10A Geldanamycin
0.12
uM
LJP6
72
hr
513 554 10473 0.0529 0.0176