LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 10885 | 10362 | 1.0506 | 1.0228 |
MCF 10A | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 513 | 10452 | 10362 | 1.0091 | 1.0037 |
MCF 10A | Nilotinib | 10 | uM | LJP5 | 72 | hr | 513 | 3764 | 10362 | 0.3636 | 0.5801 |
MCF 10A | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 513 | 9018 | 10473 | 0.8612 | 0.9324 |
MCF 10A | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 513 | 7616 | 10473 | 0.7272 | 0.8588 |
MCF 10A | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 513 | 3138 | 10473 | 0.2996 | 0.5158 |
MCF 10A | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 513 | 783 | 10473 | 0.0748 | 0.1017 |
MCF 10A | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 513 | 592 | 10473 | 0.0566 | 0.0325 |
MCF 10A | JNK-9L | 10 | uM | LJP6 | 72 | hr | 513 | 515 | 10473 | 0.0492 | 0.0005 |
MCF 10A | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 513 | 1058 | 10362 | 0.1020 | 0.1791 |
MCF 10A | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 513 | 1025 | 10473 | 0.0979 | 0.1696 |
MCF 10A | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 513 | 842 | 10362 | 0.0812 | 0.1206 |
MCF 10A | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 513 | 687 | 10473 | 0.0656 | 0.0682 |
MCF 10A | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 513 | 801 | 10362 | 0.0772 | 0.1051 |
MCF 10A | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 513 | 675 | 10473 | 0.0644 | 0.0647 |
MCF 10A | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 513 | 721 | 10362 | 0.0696 | 0.0811 |
MCF 10A | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 513 | 535 | 10473 | 0.0511 | 0.0096 |
MCF 10A | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 513 | 579 | 10362 | 0.0559 | 0.0268 |
MCF 10A | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 513 | 493 | 10473 | 0.0471 | -0.0101 |
MCF 10A | PD0325901 | 10 | uM | LJP5 | 72 | hr | 513 | 575 | 10362 | 0.0555 | 0.0255 |
MCF 10A | PD0325901 | 10 | uM | LJP6 | 72 | hr | 513 | 398 | 10473 | 0.0380 | -0.0571 |
MCF 10A | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 513 | 607 | 10362 | 0.0586 | 0.0393 |
MCF 10A | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 513 | 641 | 10473 | 0.0612 | 0.0518 |
MCF 10A | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 513 | 528 | 10362 | 0.0510 | 0.0052 |
MCF 10A | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 513 | 554 | 10473 | 0.0529 | 0.0176 |