LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 HG-5-88-01
10
uM
LJP6
 3
A19
 72
hr
 1097 1676 3696 0.4534 0.2735
BT-20 HG-6-64-01
0.04
uM
LJP6
 1
M06
 72
hr
 1097 3216 3610 0.8907 0.8697
BT-20 HG-6-64-01
0.04
uM
LJP6
 2
M06
 72
hr
 1097 3276 3713 0.8821 0.8624
BT-20 HG-6-64-01
0.04
uM
LJP6
 3
M06
 72
hr
 1097 3516 3696 0.9512 0.9437
BT-20 HG-6-64-01
0.12
uM
LJP6
 1
M05
 72
hr
 1097 2706 3610 0.7495 0.6910
BT-20 HG-6-64-01
0.12
uM
LJP6
 2
M05
 72
hr
 1097 2814 3713 0.7577 0.7082
BT-20 HG-6-64-01
0.12
uM
LJP6
 3
M05
 72
hr
 1097 2868 3696 0.7759 0.7304
BT-20 HG-6-64-01
0.37
uM
LJP6
 1
M04
 72
hr
 1097 2610 3610 0.7229 0.6558
BT-20 HG-6-64-01
0.37
uM
LJP6
 2
M04
 72
hr
 1097 2567 3713 0.6912 0.6213
BT-20 HG-6-64-01
0.37
uM
LJP6
 3
M04
 72
hr
 1097 2606 3696 0.7050 0.6383
BT-20 HG-6-64-01
1.11
uM
LJP6
 1
M03
 72
hr
 1097 2117 3610 0.5863 0.4659
BT-20 HG-6-64-01
1.11
uM
LJP6
 2
M03
 72
hr
 1097 2075 3713 0.5587 0.4365
BT-20 HG-6-64-01
1.11
uM
LJP6
 3
M03
 72
hr
 1097 1960 3696 0.5302 0.3925
BT-20 HG-6-64-01
3.33
uM
LJP6
 1
M02
 72
hr
 1097 1671 3610 0.4628 0.2773
BT-20 HG-6-64-01
3.33
uM
LJP6
 2
M02
 72
hr
 1097 1484 3713 0.3996 0.1873
BT-20 HG-6-64-01
3.33
uM
LJP6
 3
M02
 72
hr
 1097 1527 3696 0.4131 0.2076
BT-20 HG-6-64-01
10
uM
LJP6
 1
M01
 72
hr
 1097 657 3610 0.1820 -0.2581
BT-20 HG-6-64-01
10
uM
LJP6
 2
M01
 72
hr
 1097 626 3713 0.1686 -0.2732
BT-20 HG-6-64-01
10
uM
LJP6
 3
M01
 72
hr
 1097 598 3696 0.1618 -0.2928
BT-20 Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 1097 2621 3735 0.7017 0.6367
BT-20 Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 1097 2956 3877 0.7623 0.7231
BT-20 Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 1097 3103 3925 0.7905 0.7600
BT-20 Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 1097 2410 3735 0.6452 0.5608
BT-20 Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 1097 2721 3877 0.7017 0.6465
BT-20 Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 1097 2749 3925 0.7003 0.6478