LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 1097 3838 3735 1.0275 1.0310
BT-20 Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 1097 4078 3877 1.0516 1.0561
BT-20 Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 1097 3732 3925 0.9507 0.9458
BT-20 Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 1097 3807 3735 1.0192 1.0217
BT-20 Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 1097 4058 3877 1.0465 1.0505
BT-20 Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 1097 3760 3925 0.9579 0.9537
BT-20 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1097 3622 3735 0.9697 0.9655
BT-20 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1097 3770 3877 0.9722 0.9693
BT-20 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1097 3811 3925 0.9709 0.9681
BT-20 Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 1097 1074 3735 0.2875 -0.0120
BT-20 Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 1097 1071 3877 0.2762 -0.0132
BT-20 Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 1097 976 3925 0.2486 -0.0617
BT-20 JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 1097 3125 3610 0.8655 0.8388
BT-20 JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 1097 2724 3713 0.7335 0.6769
BT-20 JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 1097 3114 3696 0.8424 0.8136
BT-20 JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 1097 3105 3610 0.8600 0.8319
BT-20 JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 1097 2805 3713 0.7553 0.7051
BT-20 JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 1097 3006 3696 0.8132 0.7774
BT-20 JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 1097 1986 3610 0.5501 0.4124
BT-20 JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 1097 2000 3713 0.5385 0.4068
BT-20 JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 1097 1963 3696 0.5311 0.3937
BT-20 JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 1097 943 3610 0.2612 -0.0844
BT-20 JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 1097 983 3713 0.2647 -0.0606
BT-20 JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 1097 985 3696 0.2665 -0.0597
BT-20 JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 1097 818 3610 0.2266 -0.1571