LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 1097 2437 3925 0.6208 0.5433
BT-20 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1097 3552 3610 0.9838 0.9811
BT-20 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1097 3468 3713 0.9338 0.9237
BT-20 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1097 3549 3696 0.9601 0.9541
BT-20 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 1097 3227 3610 0.8938 0.8735
BT-20 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 1097 3190 3713 0.8590 0.8344
BT-20 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 1097 3174 3696 0.8587 0.8334
BT-20 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1097 3395 3610 0.9403 0.9296
BT-20 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1097 3249 3713 0.8749 0.8536
BT-20 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1097 3249 3696 0.8790 0.8580
BT-20 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 1097 2915 3610 0.8074 0.7658
BT-20 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 1097 3345 3713 0.9007 0.8846
BT-20 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 1097 3167 3696 0.8568 0.8311
BT-20 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1097 3059 3610 0.8472 0.8161
BT-20 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1097 3065 3713 0.8253 0.7932
BT-20 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1097 3278 3696 0.8868 0.8675
BT-20 Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 1097 2689 3610 0.7448 0.6848
BT-20 Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 1097 2450 3713 0.6597 0.5788
BT-20 Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 1097 2782 3696 0.7526 0.7006
BT-20 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1097 4017 3735 1.0754 1.0840
BT-20 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1097 4097 3877 1.0565 1.0613
BT-20 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1097 3777 3925 0.9622 0.9585
BT-20 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1097 3967 3735 1.0621 1.0693
BT-20 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1097 4377 3877 1.1287 1.1375
BT-20 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 1097 3664 3925 0.9334 0.9264