LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 1097 3635 3877 0.9374 0.9303
BT-20 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 1097 3731 3925 0.9505 0.9455
BT-20 BX-912
10
uM
LJP5
 1
L19
 72
hr
 1097 2370 3735 0.6345 0.5461
BT-20 BX-912
10
uM
LJP5
 2
L19
 72
hr
 1097 2344 3877 0.6045 0.5170
BT-20 BX-912
10
uM
LJP5
 3
L19
 72
hr
 1097 2161 3925 0.5505 0.4457
BT-20 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 1097 3597 3610 0.9962 0.9956
BT-20 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 1097 3837 3713 1.0332 1.0375
BT-20 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 1097 3694 3696 0.9993 0.9993
BT-20 Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 1097 3238 3610 0.8968 0.8772
BT-20 Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 1097 3699 3713 0.9960 0.9955
BT-20 Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 1097 3325 3696 0.8995 0.8827
BT-20 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 1097 3682 3610 1.0198 1.0229
BT-20 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 1097 3431 3713 0.9239 0.9120
BT-20 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 1097 3500 3696 0.9469 0.9386
BT-20 Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 1097 3716 3610 1.0292 1.0338
BT-20 Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 1097 3321 3713 0.8943 0.8769
BT-20 Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 1097 3632 3696 0.9826 0.9800
BT-20 Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 1097 3243 3610 0.8982 0.8789
BT-20 Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 1097 3301 3713 0.8889 0.8704
BT-20 Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 1097 3538 3696 0.9571 0.9506
BT-20 Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 1097 3540 3610 0.9805 0.9772
BT-20 Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 1097 3277 3713 0.8824 0.8627
BT-20 Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 1097 3090 3696 0.8359 0.8056
BT-20 MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1097 3405 3610 0.9431 0.9329
BT-20 MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 1097 3164 3713 0.8520 0.8259