LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 1097 2009 3610 0.5564 0.4219
BT-20 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 1097 1822 3713 0.4906 0.3342
BT-20 ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 1097 2106 3696 0.5697 0.4508
BT-20 ZSTK474
1.11
uM
LJP6
 1
M15
 72
hr
 1097 1231 3610 0.3409 0.0692
BT-20 ZSTK474
1.11
uM
LJP6
 2
M15
 72
hr
 1097 1180 3713 0.3177 0.0422
BT-20 ZSTK474
1.11
uM
LJP6
 3
M15
 72
hr
 1097 1201 3696 0.3249 0.0529
BT-20 ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 1097 1006 3610 0.2786 -0.0493
BT-20 ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 1097 994 3713 0.2677 -0.0546
BT-20 ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 1097 1151 3696 0.3114 0.0277
BT-20 ZSTK474
10
uM
LJP6
 1
M13
 72
hr
 1097 982 3610 0.2720 -0.0625
BT-20 ZSTK474
10
uM
LJP6
 2
M13
 72
hr
 1097 889 3713 0.2394 -0.1128
BT-20 ZSTK474
10
uM
LJP6
 3
M13
 72
hr
 1097 906 3696 0.2451 -0.1035
BT-20 BX-912
0.04
uM
LJP5
 1
L24
 72
hr
 1097 3358 3735 0.8990 0.8831
BT-20 BX-912
0.04
uM
LJP5
 2
L24
 72
hr
 1097 3572 3877 0.9211 0.9118
BT-20 BX-912
0.04
uM
LJP5
 3
L24
 72
hr
 1097 3507 3925 0.8934 0.8811
BT-20 BX-912
0.12
uM
LJP5
 1
L23
 72
hr
 1097 3457 3735 0.9255 0.9143
BT-20 BX-912
0.12
uM
LJP5
 2
L23
 72
hr
 1097 3505 3877 0.9039 0.8920
BT-20 BX-912
0.12
uM
LJP5
 3
L23
 72
hr
 1097 4160 3925 1.0598 1.0641
BT-20 BX-912
0.37
uM
LJP5
 1
L22
 72
hr
 1097 3384 3735 0.9060 0.8913
BT-20 BX-912
0.37
uM
LJP5
 2
L22
 72
hr
 1097 3509 3877 0.9049 0.8932
BT-20 BX-912
0.37
uM
LJP5
 3
L22
 72
hr
 1097 3956 3925 1.0078 1.0085
BT-20 BX-912
1.11
uM
LJP5
 1
L21
 72
hr
 1097 3504 3735 0.9381 0.9290
BT-20 BX-912
1.11
uM
LJP5
 2
L21
 72
hr
 1097 3543 3877 0.9137 0.9033
BT-20 BX-912
1.11
uM
LJP5
 3
L21
 72
hr
 1097 3812 3925 0.9711 0.9684
BT-20 BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 1097 3685 3735 0.9866 0.9847