LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 1097 4062 3925 1.0348 1.0375
BT-20 SB590885
10
uM
LJP5
 1
L13
 72
hr
 1097 2976 3735 0.7967 0.7587
BT-20 SB590885
10
uM
LJP5
 2
L13
 72
hr
 1097 3660 3877 0.9438 0.9375
BT-20 SB590885
10
uM
LJP5
 3
L13
 72
hr
 1097 3506 3925 0.8932 0.8808
BT-20 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 1097 2650 3610 0.7340 0.6705
BT-20 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 1097 2604 3713 0.7012 0.6345
BT-20 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1097 2976 3696 0.8051 0.7673
BT-20 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 1097 2594 3610 0.7185 0.6499
BT-20 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 1097 2418 3713 0.6511 0.5671
BT-20 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 1097 2718 3696 0.7353 0.6781
BT-20 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 1097 2009 3610 0.5564 0.4219
BT-20 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 1097 1847 3713 0.4974 0.3445
BT-20 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 1097 1716 3696 0.4642 0.2907
BT-20 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 1097 1194 3610 0.3307 0.0504
BT-20 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 1097 1277 3713 0.3439 0.0901
BT-20 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 1097 1330 3696 0.3598 0.1160
BT-20 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 1097 1052 3610 0.2914 -0.0242
BT-20 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 1097 1019 3713 0.2744 -0.0412
BT-20 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 1097 1189 3696 0.3217 0.0469
BT-20 Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 1097 797 3610 0.2207 -0.1698
BT-20 Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 1097 955 3713 0.2572 -0.0759
BT-20 Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 1097 915 3696 0.2475 -0.0985
BT-20 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 1097 3875 3735 1.0374 1.0420
BT-20 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 1097 4177 3877 1.0772 1.0833
BT-20 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 1097 4333 3925 1.1038 1.1104