LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 1097 3345 3877 0.8626 0.8441
BT-20 Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 1097 3506 3925 0.8932 0.8808
BT-20 Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 1097 3402 3735 0.9108 0.8970
BT-20 Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 1097 3762 3877 0.9701 0.9670
BT-20 Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 1097 3525 3925 0.8980 0.8863
BT-20 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1097 3110 3735 0.8326 0.8031
BT-20 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1097 3363 3877 0.8673 0.8496
BT-20 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1097 3329 3925 0.8481 0.8286
BT-20 Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 1097 2880 3735 0.7710 0.7264
BT-20 Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 1097 3053 3877 0.7873 0.7539
BT-20 Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 1097 3044 3925 0.7755 0.7417
BT-20 Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 1097 1422 3735 0.3807 0.1580
BT-20 Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 1097 1492 3877 0.3848 0.1838
BT-20 Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 1097 1786 3925 0.4550 0.3033
BT-20 Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 1097 1066 3735 0.2854 -0.0162
BT-20 Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 1097 1044 3877 0.2692 -0.0269
BT-20 Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 1097 1146 3925 0.2919 0.0239
BT-20 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 1097 3552 3610 0.9838 0.9811
BT-20 BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 1097 3691 3713 0.9939 0.9930
BT-20 BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 1097 3562 3696 0.9636 0.9582
BT-20 BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 1097 3225 3610 0.8932 0.8728
BT-20 BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 1097 3343 3713 0.9002 0.8839
BT-20 BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 1097 3697 3696 1.0002 1.0002
BT-20 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 1097 3072 3610 0.8508 0.8206
BT-20 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 1097 3131 3713 0.8431 0.8151