LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 1235 3967 4474 0.8865 0.8744
MDA-MB-231 Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 1235 4048 4578 0.8841 0.8738
MDA-MB-231 Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 1235 4529 4929 0.9188 0.9169
MDA-MB-231 Brivanib
10
uM
LJP5
 1
P13
 72
hr
 1235 3045 4474 0.6805 0.6254
MDA-MB-231 Brivanib
10
uM
LJP5
 2
P13
 72
hr
 1235 2910 4578 0.6356 0.5734
MDA-MB-231 Brivanib
10
uM
LJP5
 3
P13
 72
hr
 1235 3287 4929 0.6668 0.6325
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 1235 3900 4355 0.8953 0.8820
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 1235 3787 4277 0.8854 0.8686
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 1235 4094 4583 0.8932 0.8841
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 1235 3613 4355 0.8294 0.8044
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 1235 3625 4277 0.8475 0.8235
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 1235 4070 4583 0.8880 0.8782
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 1235 3635 4355 0.8345 0.8105
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 1235 3580 4277 0.8370 0.8108
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 1235 3979 4583 0.8681 0.8559
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 1235 3432 4355 0.7879 0.7541
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 1235 3547 4277 0.8293 0.8015
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 1235 3654 4583 0.7972 0.7741
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 1235 3424 4355 0.7861 0.7519
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 1235 3703 4277 0.8657 0.8453
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 1235 4050 4583 0.8836 0.8733
MDA-MB-231 CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 1235 3340 4355 0.7668 0.7281
MDA-MB-231 CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 1235 3371 4277 0.7881 0.7510
MDA-MB-231 CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 1235 3788 4583 0.8265 0.8082
MDA-MB-231 Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 1235 4561 4355 1.0471 1.0513