LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 1235 619 4277 0.1447 -0.3203
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 1235 631 4583 0.1377 -0.2992
MDA-MB-231 AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 1235 372 4355 0.0854 -0.4835
MDA-MB-231 AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 1235 374 4277 0.0874 -0.4870
MDA-MB-231 AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 1235 337 4583 0.0735 -0.4971
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1235 4610 4474 1.0302 1.0324
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 1235 4495 4578 0.9818 0.9806
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1235 5206 4929 1.0561 1.0555
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 1235 4200 4474 0.9386 0.9329
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 1235 4667 4578 1.0193 1.0204
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 1235 4730 4929 0.9596 0.9591
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 1235 4109 4474 0.9183 0.9102
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 1235 4019 4578 0.8778 0.8667
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 1235 4531 4929 0.9192 0.9173
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 1235 2922 4474 0.6530 0.5897
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 1235 2969 4578 0.6485 0.5902
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 1235 3523 4929 0.7147 0.6902
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 1235 1426 4474 0.3187 0.0801
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 1235 1533 4578 0.3348 0.1208
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 1235 1784 4929 0.3619 0.2019
MDA-MB-231 Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 1235 779 4474 0.1741 -0.2202
MDA-MB-231 Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 1235 742 4578 0.1621 -0.2367
MDA-MB-231 Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 1235 748 4929 0.1518 -0.2225
MDA-MB-231 Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 1235 764 4474 0.1707 -0.2283
MDA-MB-231 Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 1235 910 4578 0.1988 -0.1496