LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Linsitinib | 10 | uM | LJP5 | 1 | O19 | 72 | hr | 1389 | 2655 | 5772 | 0.4599 | 0.3706 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 3 | O19 | 72 | hr | 1389 | 2664 | 6038 | 0.4412 | 0.3596 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 1 | O18 | 72 | hr | 1389 | 5914 | 5772 | 1.0245 | 1.0237 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 3 | O18 | 72 | hr | 1389 | 5607 | 6038 | 0.9285 | 0.9313 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 1 | O17 | 72 | hr | 1389 | 5552 | 5772 | 0.9618 | 0.9625 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 3 | O17 | 72 | hr | 1389 | 5335 | 6038 | 0.8835 | 0.8865 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 1 | O16 | 72 | hr | 1389 | 5785 | 5772 | 1.0022 | 1.0021 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 3 | O16 | 72 | hr | 1389 | 5577 | 6038 | 0.9236 | 0.9264 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 1 | O15 | 72 | hr | 1389 | 5910 | 5772 | 1.0238 | 1.0230 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 3 | O15 | 72 | hr | 1389 | 6703 | 6038 | 1.1100 | 1.1010 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 1 | O14 | 72 | hr | 1389 | 6067 | 5772 | 1.0510 | 1.0490 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 3 | O14 | 72 | hr | 1389 | 6254 | 6038 | 1.0357 | 1.0334 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 1 | O13 | 72 | hr | 1389 | 4933 | 5772 | 0.8546 | 0.8528 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 3 | O13 | 72 | hr | 1389 | 5018 | 6038 | 0.8310 | 0.8328 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 1 | P12 | 72 | hr | 1389 | 5425 | 5772 | 0.9398 | 0.9405 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 3 | P12 | 72 | hr | 1389 | 5641 | 6038 | 0.9342 | 0.9368 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 1 | P11 | 72 | hr | 1389 | 5863 | 5772 | 1.0157 | 1.0152 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 3 | P11 | 72 | hr | 1389 | 5545 | 6038 | 0.9183 | 0.9212 |
| MCF7 | Momelotinib | 0.37 | uM | LJP5 | 1 | P10 | 72 | hr | 1389 | 5543 | 5772 | 0.9602 | 0.9609 |
| MCF7 | Momelotinib | 0.37 | uM | LJP5 | 3 | P10 | 72 | hr | 1389 | 5244 | 6038 | 0.8684 | 0.8713 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 1 | P09 | 72 | hr | 1389 | 4320 | 5772 | 0.7484 | 0.7369 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 3 | P09 | 72 | hr | 1389 | 4336 | 6038 | 0.7181 | 0.7107 |
| MCF7 | Momelotinib | 3.33 | uM | LJP5 | 1 | P08 | 72 | hr | 1389 | 3366 | 5772 | 0.5831 | 0.5383 |
| MCF7 | Momelotinib | 3.33 | uM | LJP5 | 3 | P08 | 72 | hr | 1389 | 3667 | 6038 | 0.6073 | 0.5807 |
| MCF7 | Momelotinib | 10 | uM | LJP5 | 1 | P07 | 72 | hr | 1389 | 1596 | 5772 | 0.2765 | 0.0699 |