LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 WZ3105
0.37
uM
LJP5
 72
hr
 1311 807 5013 0.1611 -0.1362
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 72
hr
 1311 3616 5013 0.7214 0.6227
MDA-MB-231 Y39983
0.37
uM
LJP6
 72
hr
 1311 4370 5013 0.8718 0.8263
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 1311 4674 5013 0.9323 0.9084
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 1311 3694 5013 0.7369 0.6436
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 1311 3443 5013 0.6867 0.5757
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 1311 4347 5013 0.8671 0.8200
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 72
hr
 1311 748 5013 0.1493 -0.1521
MDA-MB-231 AT-7519
1.11
uM
LJP6
 72
hr
 1311 745 5013 0.1486 -0.1531
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 72
hr
 1311 1274 5013 0.2542 -0.0101
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 72
hr
 1311 4174 5013 0.8326 0.7732
MDA-MB-231 AZD7762
1.11
uM
LJP6
 72
hr
 1311 1235 5013 0.2464 -0.0206
MDA-MB-231 AZD8055
1.11
uM
LJP6
 72
hr
 1311 1938 5013 0.3867 0.1694
MDA-MB-231 AZD8330
1.11
uM
LJP5
 72
hr
 1311 1514 5013 0.3021 0.0548
MDA-MB-231 Barasertib
1.11
uM
LJP5
 72
hr
 1311 1656 5013 0.3304 0.0931
MDA-MB-231 BI-2536
1.11
uM
LJP6
 72
hr
 1311 1276 5013 0.2546 -0.0096
MDA-MB-231 BMS345541
1.11
uM
LJP6
 72
hr
 1311 3794 5013 0.7569 0.6707
MDA-MB-231 SNS-032
1.11
uM
LJP6
 72
hr
 1311 763 5013 0.1522 -0.1482
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 72
hr
 1311 2456 5013 0.4899 0.3092
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 72
hr
 1311 4552 5013 0.9081 0.8755
MDA-MB-231 SB590885
1.11
uM
LJP5
 72
hr
 1311 4651 5013 0.9278 0.9022
MDA-MB-231 PIK-93
1.11
uM
LJP5
 72
hr
 1311 4779 5013 0.9534 0.9368
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 72
hr
 1311 4238 5013 0.8455 0.7907
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 72
hr
 1311 4882 5013 0.9738 0.9645
MDA-MB-231 Luminespib
1.11
uM
LJP5
 72
hr
 1311 1019 5013 0.2033 -0.0790