LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | QL-XII-47 | 10.0 | uM | LJP6 | 2 | O19 | 72 | hr | 1235 | 1218 | 4156 | 0.2931 | -0.0060 |
| MCF7 | QL-XII-47 | 10.0 | uM | LJP6 | 3 | O19 | 72 | hr | 1235 | 944 | 4156 | 0.2271 | -0.0998 |
| MCF7 | Radicicol | 10.0 | uM | LJP5 | 1 | K07 | 72 | hr | 1235 | 1006 | 4156 | 0.2421 | -0.0785 |
| MCF7 | Radicicol | 10.0 | uM | LJP5 | 2 | K07 | 72 | hr | 1235 | 972 | 4156 | 0.2339 | -0.0902 |
| MCF7 | Radicicol | 10.0 | uM | LJP5 | 3 | K07 | 72 | hr | 1235 | 1018 | 4156 | 0.2449 | -0.0744 |
| MCF7 | Radicicol | 10.0 | uM | LJP6 | 1 | K07 | 72 | hr | 1235 | 990 | 4156 | 0.2382 | -0.0840 |
| MCF7 | Radicicol | 10.0 | uM | LJP6 | 2 | K07 | 72 | hr | 1235 | 981 | 4156 | 0.2360 | -0.0871 |
| MCF7 | Radicicol | 10.0 | uM | LJP6 | 3 | K07 | 72 | hr | 1235 | 872 | 4156 | 0.2098 | -0.1244 |
| MCF7 | Seliciclib | 10.0 | uM | LJP5 | 1 | J01 | 72 | hr | 1235 | 734 | 4156 | 0.1766 | -0.1717 |
| MCF7 | Seliciclib | 10.0 | uM | LJP5 | 2 | J01 | 72 | hr | 1235 | 687 | 4156 | 0.1653 | -0.1878 |
| MCF7 | Seliciclib | 10.0 | uM | LJP5 | 3 | J01 | 72 | hr | 1235 | 697 | 4156 | 0.1677 | -0.1843 |
| MCF7 | Ruxolitinib | 10.0 | uM | LJP5 | 1 | O13 | 72 | hr | 1235 | 2940 | 4156 | 0.7074 | 0.5836 |
| MCF7 | Ruxolitinib | 10.0 | uM | LJP5 | 2 | O13 | 72 | hr | 1235 | 3122 | 4156 | 0.7512 | 0.6459 |
| MCF7 | Ruxolitinib | 10.0 | uM | LJP5 | 3 | O13 | 72 | hr | 1235 | 3490 | 4156 | 0.8397 | 0.7719 |
| MCF7 | XL147 | 10.0 | uM | LJP5 | 1 | G07 | 72 | hr | 1235 | 2775 | 4156 | 0.6677 | 0.5271 |
| MCF7 | XL147 | 10.0 | uM | LJP5 | 2 | G07 | 72 | hr | 1235 | 2521 | 4156 | 0.6066 | 0.4402 |
| MCF7 | XL147 | 10.0 | uM | LJP5 | 3 | G07 | 72 | hr | 1235 | 2775 | 4156 | 0.6677 | 0.5271 |
| MCF7 | Saracatinib | 10.0 | uM | LJP6 | 1 | D07 | 72 | hr | 1235 | 1562 | 4156 | 0.3758 | 0.1118 |
| MCF7 | Saracatinib | 10.0 | uM | LJP6 | 2 | D07 | 72 | hr | 1235 | 1922 | 4156 | 0.4625 | 0.2351 |
| MCF7 | Saracatinib | 10.0 | uM | LJP6 | 3 | D07 | 72 | hr | 1235 | 1626 | 4156 | 0.3912 | 0.1337 |
| MCF7 | Selumetinib | 10.0 | uM | LJP6 | 1 | M07 | 72 | hr | 1235 | 2757 | 4156 | 0.6634 | 0.5210 |
| MCF7 | Selumetinib | 10.0 | uM | LJP6 | 2 | M07 | 72 | hr | 1235 | 2466 | 4156 | 0.5933 | 0.4213 |
| MCF7 | Selumetinib | 10.0 | uM | LJP6 | 3 | M07 | 72 | hr | 1235 | 2580 | 4156 | 0.6208 | 0.4604 |
| MCF7 | Sirolimus | 10.0 | uM | LJP6 | 1 | L13 | 72 | hr | 1235 | 2613 | 4156 | 0.6287 | 0.4717 |
| MCF7 | Sirolimus | 10.0 | uM | LJP6 | 2 | L13 | 72 | hr | 1235 | 2339 | 4156 | 0.5628 | 0.3779 |