LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | NU7441 | 10.0 | uM | LJP5 | 3 | C07 | 72 | hr | 1235 | 1595 | 4156 | 0.3838 | 0.1231 |
| MCF7 | Dactolisib | 10.0 | uM | LJP5 | 1 | M13 | 72 | hr | 1235 | 1316 | 4156 | 0.3166 | 0.0276 |
| MCF7 | Dactolisib | 10.0 | uM | LJP5 | 2 | M13 | 72 | hr | 1235 | 1352 | 4156 | 0.3253 | 0.0399 |
| MCF7 | Dactolisib | 10.0 | uM | LJP5 | 3 | M13 | 72 | hr | 1235 | 1317 | 4156 | 0.3169 | 0.0279 |
| MCF7 | NVP-TAE684 | 10.0 | uM | LJP6 | 1 | K13 | 72 | hr | 1235 | 1171 | 4156 | 0.2818 | -0.0220 |
| MCF7 | NVP-TAE684 | 10.0 | uM | LJP6 | 2 | K13 | 72 | hr | 1235 | 1142 | 4156 | 0.2748 | -0.0320 |
| MCF7 | NVP-TAE684 | 10.0 | uM | LJP6 | 3 | K13 | 72 | hr | 1235 | 1193 | 4156 | 0.2870 | -0.0145 |
| MCF7 | Palbociclib | 10.0 | uM | LJP6 | 1 | E13 | 72 | hr | 1235 | 1921 | 4156 | 0.4622 | 0.2347 |
| MCF7 | Palbociclib | 10.0 | uM | LJP6 | 2 | E13 | 72 | hr | 1235 | 1953 | 4156 | 0.4699 | 0.2457 |
| MCF7 | Palbociclib | 10.0 | uM | LJP6 | 3 | E13 | 72 | hr | 1235 | 2026 | 4156 | 0.4875 | 0.2707 |
| MCF7 | PD0325901 | 10.0 | uM | LJP5 | 1 | C01 | 72 | hr | 1235 | 1164 | 4156 | 0.2801 | -0.0244 |
| MCF7 | PD0325901 | 10.0 | uM | LJP5 | 2 | C01 | 72 | hr | 1235 | 1162 | 4156 | 0.2796 | -0.0251 |
| MCF7 | PD0325901 | 10.0 | uM | LJP5 | 3 | C01 | 72 | hr | 1235 | 1179 | 4156 | 0.2837 | -0.0193 |
| MCF7 | PD0325901 | 10.0 | uM | LJP6 | 1 | E01 | 72 | hr | 1235 | 1120 | 4156 | 0.2695 | -0.0395 |
| MCF7 | PD0325901 | 10.0 | uM | LJP6 | 2 | E01 | 72 | hr | 1235 | 1129 | 4156 | 0.2716 | -0.0364 |
| MCF7 | PD0325901 | 10.0 | uM | LJP6 | 3 | E01 | 72 | hr | 1235 | 1065 | 4156 | 0.2563 | -0.0583 |
| MCF7 | PD173074 | 10.0 | uM | LJP6 | 1 | I07 | 72 | hr | 1235 | 3203 | 4156 | 0.7707 | 0.6737 |
| MCF7 | PD173074 | 10.0 | uM | LJP6 | 2 | I07 | 72 | hr | 1235 | 2874 | 4156 | 0.6915 | 0.5610 |
| MCF7 | PD173074 | 10.0 | uM | LJP6 | 3 | I07 | 72 | hr | 1235 | 3312 | 4156 | 0.7969 | 0.7110 |
| MCF7 | PD184352 | 10.0 | uM | LJP5 | 1 | L07 | 72 | hr | 1235 | 1876 | 4156 | 0.4514 | 0.2193 |
| MCF7 | PD184352 | 10.0 | uM | LJP5 | 2 | L07 | 72 | hr | 1235 | 1975 | 4156 | 0.4752 | 0.2532 |
| MCF7 | PD184352 | 10.0 | uM | LJP5 | 3 | L07 | 72 | hr | 1235 | 2371 | 4156 | 0.5705 | 0.3888 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 1 | I13 | 72 | hr | 1235 | 1224 | 4156 | 0.2945 | -0.0039 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 2 | I13 | 72 | hr | 1235 | 944 | 4156 | 0.2271 | -0.0998 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 3 | I13 | 72 | hr | 1235 | 1079 | 4156 | 0.2596 | -0.0535 |