LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 10.0 | uM | LJP5 | 2 | K19 | 72 | hr | 1235 | 1214 | 4156 | 0.2921 | -0.0073 |
| MCF7 | GDC-0980 | 10.0 | uM | LJP5 | 3 | K19 | 72 | hr | 1235 | 1129 | 4156 | 0.2716 | -0.0364 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 1 | E13 | 72 | hr | 1235 | 1143 | 4156 | 0.2750 | -0.0316 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 2 | E13 | 72 | hr | 1235 | 1107 | 4156 | 0.2664 | -0.0440 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 3 | E13 | 72 | hr | 1235 | 894 | 4156 | 0.2151 | -0.1169 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 1 | L13 | 72 | hr | 1235 | 2593 | 4156 | 0.6239 | 0.4648 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 2 | L13 | 72 | hr | 1235 | 2685 | 4156 | 0.6460 | 0.4963 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 3 | L13 | 72 | hr | 1235 | 2828 | 4156 | 0.6804 | 0.5453 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 1 | K13 | 72 | hr | 1235 | 1465 | 4156 | 0.3525 | 0.0786 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 2 | K13 | 72 | hr | 1235 | 1457 | 4156 | 0.3506 | 0.0759 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 3 | K13 | 72 | hr | 1235 | 1331 | 4156 | 0.3203 | 0.0327 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 1 | C07 | 72 | hr | 1235 | 1731 | 4156 | 0.4165 | 0.1697 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 2 | C07 | 72 | hr | 1235 | 1691 | 4156 | 0.4069 | 0.1560 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 3 | C07 | 72 | hr | 1235 | 1873 | 4156 | 0.4507 | 0.2183 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 1 | N01 | 72 | hr | 1235 | 1073 | 4156 | 0.2582 | -0.0556 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 2 | N01 | 72 | hr | 1235 | 1074 | 4156 | 0.2584 | -0.0553 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 3 | N01 | 72 | hr | 1235 | 984 | 4156 | 0.2368 | -0.0861 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 1 | H13 | 72 | hr | 1235 | 1151 | 4156 | 0.2769 | -0.0289 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 2 | H13 | 72 | hr | 1235 | 1237 | 4156 | 0.2976 | 0.0006 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 3 | H13 | 72 | hr | 1235 | 1311 | 4156 | 0.3154 | 0.0259 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 1235 | 735 | 4156 | 0.1769 | -0.1713 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 1235 | 652 | 4156 | 0.1569 | -0.1997 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 3 | I19 | 72 | hr | 1235 | 859 | 4156 | 0.2067 | -0.1289 |
| MCF7 | OSI-027 | 10.0 | uM | LJP6 | 1 | E07 | 72 | hr | 1235 | 1517 | 4156 | 0.3650 | 0.0964 |
| MCF7 | OSI-027 | 10.0 | uM | LJP6 | 2 | E07 | 72 | hr | 1235 | 1650 | 4156 | 0.3970 | 0.1420 |