LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1235 1359 4156 0.3270 0.0423
MCF7 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1235 1423 4156 0.3424 0.0642
MCF7 Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 1235 2362 4156 0.5683 0.3857
MCF7 Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 1235 2399 4156 0.5772 0.3984
MCF7 Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 1235 2162 4156 0.5202 0.3173
MCF7 TWS119
3.33
uM
LJP5
 1
M02
 72
hr
 1235 2621 4156 0.6306 0.4744
MCF7 TWS119
3.33
uM
LJP5
 2
M02
 72
hr
 1235 2678 4156 0.6443 0.4939
MCF7 TWS119
3.33
uM
LJP5
 3
M02
 72
hr
 1235 2596 4156 0.6246 0.4658
MCF7 Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 1235 4321 4156 1.0397 1.0564
MCF7 Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 1235 4092 4156 0.9846 0.9780
MCF7 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1235 4066 4156 0.9783 0.9691
MCF7 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1235 1097 4156 0.2640 -0.0474
MCF7 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1235 1021 4156 0.2457 -0.0734
MCF7 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1235 987 4156 0.2375 -0.0850
MCF7 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1235 956 4156 0.2300 -0.0957
MCF7 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1235 1078 4156 0.2594 -0.0539
MCF7 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1235 1119 4156 0.2692 -0.0398
MCF7 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1235 1710 4156 0.4114 0.1625
MCF7 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1235 1681 4156 0.4045 0.1526
MCF7 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1235 1606 4156 0.3864 0.1269
MCF7 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 1235 849 4156 0.2043 -0.1323
MCF7 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 1235 779 4156 0.1874 -0.1563
MCF7 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 1235 845 4156 0.2033 -0.1337
MCF7 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1235 1649 4156 0.3968 0.1416
MCF7 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1235 1613 4156 0.3881 0.1293