LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 3 | D02 | 72 | hr | 1235 | 985 | 4156 | 0.2370 | -0.0857 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 1 | H14 | 72 | hr | 1235 | 516 | 4156 | 0.1242 | -0.2463 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1235 | 557 | 4156 | 0.1340 | -0.2323 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 3 | H14 | 72 | hr | 1235 | 664 | 4156 | 0.1598 | -0.1956 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 1 | K20 | 72 | hr | 1235 | 1120 | 4156 | 0.2695 | -0.0395 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 2 | K20 | 72 | hr | 1235 | 1203 | 4156 | 0.2895 | -0.0111 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1235 | 1179 | 4156 | 0.2837 | -0.0193 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 1 | E14 | 72 | hr | 1235 | 2326 | 4156 | 0.5597 | 0.3734 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 2 | E14 | 72 | hr | 1235 | 2121 | 4156 | 0.5103 | 0.3032 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 3 | E14 | 72 | hr | 1235 | 2190 | 4156 | 0.5269 | 0.3268 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 1 | L14 | 72 | hr | 1235 | 4484 | 4156 | 1.0789 | 1.1122 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 2 | L14 | 72 | hr | 1235 | 5054 | 4156 | 1.2160 | 1.3074 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 3 | L14 | 72 | hr | 1235 | 4564 | 4156 | 1.0981 | 1.1396 |
| MCF7 | PIK-93 | 3.33 | uM | LJP5 | 1 | K14 | 72 | hr | 1235 | 2325 | 4156 | 0.5594 | 0.3731 |
| MCF7 | PIK-93 | 3.33 | uM | LJP5 | 2 | K14 | 72 | hr | 1235 | 2555 | 4156 | 0.6148 | 0.4518 |
| MCF7 | PIK-93 | 3.33 | uM | LJP5 | 3 | K14 | 72 | hr | 1235 | 2436 | 4156 | 0.5861 | 0.4111 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 1 | C08 | 72 | hr | 1235 | 3556 | 4156 | 0.8556 | 0.7945 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 2 | C08 | 72 | hr | 1235 | 3282 | 4156 | 0.7897 | 0.7007 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 3 | C08 | 72 | hr | 1235 | 3475 | 4156 | 0.8361 | 0.7668 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1235 | 1655 | 4156 | 0.3982 | 0.1437 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 1235 | 1654 | 4156 | 0.3980 | 0.1433 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1235 | 1787 | 4156 | 0.4300 | 0.1889 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 1 | H14 | 72 | hr | 1235 | 1347 | 4156 | 0.3241 | 0.0382 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 2 | H14 | 72 | hr | 1235 | 1397 | 4156 | 0.3361 | 0.0553 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 3 | H14 | 72 | hr | 1235 | 1422 | 4156 | 0.3421 | 0.0639 |