LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 2 | M21 | 72 | hr | 1235 | 4469 | 4156 | 1.0753 | 1.1071 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 3 | M21 | 72 | hr | 1235 | 4622 | 4156 | 1.1121 | 1.1595 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 1 | H09 | 72 | hr | 1235 | 1313 | 4156 | 0.3159 | 0.0266 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 2 | H09 | 72 | hr | 1235 | 1433 | 4156 | 0.3448 | 0.0677 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 3 | H09 | 72 | hr | 1235 | 1491 | 4156 | 0.3587 | 0.0875 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 1 | C15 | 72 | hr | 1235 | 3627 | 4156 | 0.8727 | 0.8188 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 2 | C15 | 72 | hr | 1235 | 3880 | 4156 | 0.9336 | 0.9055 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 3 | C15 | 72 | hr | 1235 | 3693 | 4156 | 0.8886 | 0.8414 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 1 | D21 | 72 | hr | 1235 | 1253 | 4156 | 0.3015 | 0.0060 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 2 | D21 | 72 | hr | 1235 | 1248 | 4156 | 0.3003 | 0.0043 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 3 | D21 | 72 | hr | 1235 | 1134 | 4156 | 0.2729 | -0.0347 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 1 | N09 | 72 | hr | 1235 | 4820 | 4156 | 1.1597 | 1.2273 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 2 | N09 | 72 | hr | 1235 | 4237 | 4156 | 1.0194 | 1.0277 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 3 | N09 | 72 | hr | 1235 | 4667 | 4156 | 1.1229 | 1.1749 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 1 | O03 | 72 | hr | 1235 | 1393 | 4156 | 0.3352 | 0.0540 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 2 | O03 | 72 | hr | 1235 | 1397 | 4156 | 0.3361 | 0.0553 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 3 | O03 | 72 | hr | 1235 | 1323 | 4156 | 0.3183 | 0.0300 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 1 | O03 | 72 | hr | 1235 | 1293 | 4156 | 0.3111 | 0.0197 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 2 | O03 | 72 | hr | 1235 | 1517 | 4156 | 0.3650 | 0.0964 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 3 | O03 | 72 | hr | 1235 | 1546 | 4156 | 0.3720 | 0.1064 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 1 | E03 | 72 | hr | 1235 | 1569 | 4156 | 0.3775 | 0.1142 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 2 | E03 | 72 | hr | 1235 | 1758 | 4156 | 0.4230 | 0.1789 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 3 | E03 | 72 | hr | 1235 | 1678 | 4156 | 0.4037 | 0.1515 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP6 | 1 | C03 | 72 | hr | 1235 | 1715 | 4156 | 0.4126 | 0.1642 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP6 | 2 | C03 | 72 | hr | 1235 | 1821 | 4156 | 0.4381 | 0.2005 |