LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 3 | M09 | 72 | hr | 1235 | 1758 | 4156 | 0.4230 | 0.1789 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 1 | P15 | 72 | hr | 1235 | 3553 | 4156 | 0.8549 | 0.7935 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 2 | P15 | 72 | hr | 1235 | 3387 | 4156 | 0.8149 | 0.7367 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 3 | P15 | 72 | hr | 1235 | 4061 | 4156 | 0.9771 | 0.9674 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 1 | H03 | 72 | hr | 1235 | 864 | 4156 | 0.2079 | -0.1272 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 2 | H03 | 72 | hr | 1235 | 944 | 4156 | 0.2271 | -0.0998 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 3 | H03 | 72 | hr | 1235 | 999 | 4156 | 0.2404 | -0.0809 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 1 | L21 | 72 | hr | 1235 | 2461 | 4156 | 0.5921 | 0.4196 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 2 | L21 | 72 | hr | 1235 | 2147 | 4156 | 0.5166 | 0.3121 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 3 | L21 | 72 | hr | 1235 | 2443 | 4156 | 0.5878 | 0.4135 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 1 | H09 | 72 | hr | 1235 | 2559 | 4156 | 0.6157 | 0.4532 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 2 | H09 | 72 | hr | 1235 | 3007 | 4156 | 0.7235 | 0.6066 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 3 | H09 | 72 | hr | 1235 | 2796 | 4156 | 0.6727 | 0.5343 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1235 | 1285 | 4156 | 0.3092 | 0.0170 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 2 | G09 | 72 | hr | 1235 | 1263 | 4156 | 0.3039 | 0.0095 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 3 | G09 | 72 | hr | 1235 | 1392 | 4156 | 0.3349 | 0.0536 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 1 | F03 | 72 | hr | 1235 | 932 | 4156 | 0.2243 | -0.1039 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 2 | F03 | 72 | hr | 1235 | 659 | 4156 | 0.1586 | -0.1973 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 3 | F03 | 72 | hr | 1235 | 994 | 4156 | 0.2392 | -0.0826 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 1235 | 555 | 4156 | 0.1335 | -0.2330 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 2 | G03 | 72 | hr | 1235 | 529 | 4156 | 0.1273 | -0.2419 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 1235 | 569 | 4156 | 0.1369 | -0.2282 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 1 | P15 | 72 | hr | 1235 | 2666 | 4156 | 0.6415 | 0.4898 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 2 | P15 | 72 | hr | 1235 | 2481 | 4156 | 0.5969 | 0.4265 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 3 | P15 | 72 | hr | 1235 | 2219 | 4156 | 0.5339 | 0.3368 |