LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 1235 3984 4156 0.9586 0.9411
MCF7 Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 1235 3642 4156 0.8763 0.8240
MCF7 Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 1235 3897 4156 0.9376 0.9113
MCF7 Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 1235 4382 4156 1.0543 1.0773
MCF7 XL147
0.37
uM
LJP5
 1
G10
 72
hr
 1235 4602 4156 1.1073 1.1526
MCF7 XL147
0.37
uM
LJP5
 2
G10
 72
hr
 1235 4472 4156 1.0760 1.1081
MCF7 XL147
0.37
uM
LJP5
 3
G10
 72
hr
 1235 4553 4156 1.0955 1.1359
MCF7 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1235 2209 4156 0.5315 0.3333
MCF7 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1235 1885 4156 0.4535 0.2224
MCF7 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1235 1947 4156 0.4685 0.2436
MCF7 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 1235 3181 4156 0.7654 0.6661
MCF7 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 1235 2543 4156 0.6119 0.4477
MCF7 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 1235 2913 4156 0.7009 0.5744
MCF7 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 1235 2543 4156 0.6119 0.4477
MCF7 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 1235 2222 4156 0.5346 0.3378
MCF7 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 1235 2732 4156 0.6573 0.5124
MCF7 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 1235 3940 4156 0.9480 0.9260
MCF7 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1235 4099 4156 0.9863 0.9804
MCF7 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 1235 3685 4156 0.8866 0.8387
MCF7 SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 1235 4510 4156 1.0851 1.1211
MCF7 SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 1235 4606 4156 1.1082 1.1540
MCF7 SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 1235 4675 4156 1.1248 1.1776
MCF7 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1235 3580 4156 0.8614 0.8027
MCF7 Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 1235 3836 4156 0.9230 0.8904
MCF7 Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 1235 3122 4156 0.7512 0.6459