LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 1235 1186 4156 0.2854 -0.0169
MCF7 MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 1235 1472 4156 0.3542 0.0810
MCF7 MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 1235 1652 4156 0.3975 0.1426
MCF7 MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 1235 1736 4156 0.4177 0.1714
MCF7 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 1235 2722 4156 0.6549 0.5090
MCF7 Neratinib
0.37
uM
LJP5
 2
A16
 72
hr
 1235 2818 4156 0.6780 0.5419
MCF7 Neratinib
0.37
uM
LJP5
 3
A16
 72
hr
 1235 2527 4156 0.6080 0.4422
MCF7 Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 1235 3762 4156 0.9052 0.8651
MCF7 Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 1235 4513 4156 1.0859 1.1222
MCF7 Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 1235 4495 4156 1.0815 1.1160
MCF7 Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 1235 2977 4156 0.7163 0.5963
MCF7 Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 1235 2577 4156 0.6200 0.4593
MCF7 Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 1235 2823 4156 0.6792 0.5436
MCF7 NU7441
0.37
uM
LJP5
 1
C10
 72
hr
 1235 4227 4156 1.0170 1.0243
MCF7 NU7441
0.37
uM
LJP5
 2
C10
 72
hr
 1235 4065 4156 0.9781 0.9688
MCF7 NU7441
0.37
uM
LJP5
 3
C10
 72
hr
 1235 4399 4156 1.0584 1.0831
MCF7 Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 1235 1534 4156 0.3691 0.1022
MCF7 Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 1235 1751 4156 0.4213 0.1765
MCF7 Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 1235 1752 4156 0.4215 0.1769
MCF7 NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 1235 1228 4156 0.2955 -0.0025
MCF7 NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 1235 1154 4156 0.2777 -0.0279
MCF7 NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 1235 1206 4156 0.2902 -0.0101
MCF7 Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 1235 1899 4156 0.4569 0.2272
MCF7 Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 1235 2338 4156 0.5625 0.3775
MCF7 Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 1235 2135 4156 0.5137 0.3080