LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1235 | 4054 | 4156 | 0.9754 | 0.9650 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 1 | F05 | 72 | hr | 1235 | 702 | 4156 | 0.1689 | -0.1826 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 2 | F05 | 72 | hr | 1235 | 837 | 4156 | 0.2014 | -0.1364 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 3 | F05 | 72 | hr | 1235 | 783 | 4156 | 0.1884 | -0.1549 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 1 | G05 | 72 | hr | 1235 | 582 | 4156 | 0.1400 | -0.2237 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 2 | G05 | 72 | hr | 1235 | 630 | 4156 | 0.1516 | -0.2073 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 3 | G05 | 72 | hr | 1235 | 550 | 4156 | 0.1323 | -0.2347 |
| MCF7 | CHIR-99021 | 0.12 | uM | LJP6 | 1 | P17 | 72 | hr | 1235 | 3453 | 4156 | 0.8308 | 0.7593 |
| MCF7 | CHIR-99021 | 0.12 | uM | LJP6 | 2 | P17 | 72 | hr | 1235 | 3235 | 4156 | 0.7784 | 0.6846 |
| MCF7 | CHIR-99021 | 0.12 | uM | LJP6 | 3 | P17 | 72 | hr | 1235 | 3033 | 4156 | 0.7298 | 0.6155 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 1 | A11 | 72 | hr | 1235 | 3397 | 4156 | 0.8173 | 0.7401 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 2 | A11 | 72 | hr | 1235 | 3229 | 4156 | 0.7769 | 0.6826 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 3 | A11 | 72 | hr | 1235 | 3463 | 4156 | 0.8332 | 0.7627 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 1 | I11 | 72 | hr | 1235 | 4392 | 4156 | 1.0567 | 1.0807 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 2 | I11 | 72 | hr | 1235 | 4834 | 4156 | 1.1631 | 1.2321 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 3 | I11 | 72 | hr | 1235 | 4387 | 4156 | 1.0555 | 1.0790 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 1 | A23 | 72 | hr | 1235 | 3070 | 4156 | 0.7387 | 0.6281 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 2 | A23 | 72 | hr | 1235 | 2970 | 4156 | 0.7146 | 0.5939 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 3 | A23 | 72 | hr | 1235 | 3145 | 4156 | 0.7567 | 0.6538 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 1 | P11 | 72 | hr | 1235 | 3349 | 4156 | 0.8058 | 0.7237 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 2 | P11 | 72 | hr | 1235 | 3526 | 4156 | 0.8484 | 0.7843 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 3 | P11 | 72 | hr | 1235 | 3559 | 4156 | 0.8563 | 0.7956 |
| MCF7 | Dasatinib | 0.12 | uM | LJP5 | 1 | D05 | 72 | hr | 1235 | 1295 | 4156 | 0.3116 | 0.0204 |
| MCF7 | Dasatinib | 0.12 | uM | LJP5 | 2 | D05 | 72 | hr | 1235 | 1226 | 4156 | 0.2950 | -0.0032 |
| MCF7 | Dasatinib | 0.12 | uM | LJP5 | 3 | D05 | 72 | hr | 1235 | 1300 | 4156 | 0.3128 | 0.0221 |