LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Neratinib
0.12
uM
LJP5
2
A17
72
hr
1657 4442 5505 0.8068 0.7236
BT-20 Neratinib
0.12
uM
LJP5
3
A17
72
hr
1657 4415 5505 0.8019 0.7166
BT-20 Nilotinib
0.12
uM
LJP5
1
N17
72
hr
1657 5349 5505 0.9715 0.9593
BT-20 Nilotinib
0.12
uM
LJP5
2
N17
72
hr
1657 5368 5505 0.9750 0.9642
BT-20 Nilotinib
0.12
uM
LJP5
3
N17
72
hr
1657 5486 5505 0.9964 0.9949
BT-20 Nintedanib
0.12
uM
LJP6
1
H05
72
hr
1657 5702 5505 1.0357 1.0510
BT-20 Nintedanib
0.12
uM
LJP6
2
H05
72
hr
1657 5736 5505 1.0418 1.0599
BT-20 Nintedanib
0.12
uM
LJP6
3
H05
72
hr
1657 5767 5505 1.0475 1.0679
BT-20 NU7441
0.12
uM
LJP5
1
C11
72
hr
1657 6003 5505 1.0903 1.1292
BT-20 NU7441
0.12
uM
LJP5
2
C11
72
hr
1657 5579 5505 1.0133 1.0191
BT-20 NU7441
0.12
uM
LJP5
3
C11
72
hr
1657 6126 5505 1.1127 1.1612
BT-20 Dactolisib
0.12
uM
LJP5
1
M17
72
hr
1657 2358 5505 0.4283 0.1820
BT-20 Dactolisib
0.12
uM
LJP5
2
M17
72
hr
1657 2363 5505 0.4292 0.1833
BT-20 Dactolisib
0.12
uM
LJP5
3
M17
72
hr
1657 2317 5505 0.4208 0.1713
BT-20 NVP-TAE684
0.12
uM
LJP6
1
K17
72
hr
1657 3833 5505 0.6962 0.5653
BT-20 NVP-TAE684
0.12
uM
LJP6
2
K17
72
hr
1657 3721 5505 0.6759 0.5362
BT-20 NVP-TAE684
0.12
uM
LJP6
3
K17
72
hr
1657 3623 5505 0.6581 0.5107
BT-20 Palbociclib
0.12
uM
LJP6
1
E17
72
hr
1657 3423 5505 0.6217 0.4588
BT-20 Palbociclib
0.12
uM
LJP6
2
E17
72
hr
1657 3149 5505 0.5720 0.3876
BT-20 Palbociclib
0.12
uM
LJP6
3
E17
72
hr
1657 3689 5505 0.6700 0.5279
BT-20 PD0325901
0.12
uM
LJP5
1
C05
72
hr
1657 5215 5505 0.9472 0.9245
BT-20 PD0325901
0.12
uM
LJP5
2
C05
72
hr
1657 4871 5505 0.8847 0.8351
BT-20 PD0325901
0.12
uM
LJP5
3
C05
72
hr
1657 4963 5505 0.9014 0.8590
BT-20 PD0325901
0.12
uM
LJP6
1
E05
72
hr
1657 4692 5505 0.8522 0.7885
BT-20 PD0325901
0.12
uM
LJP6
2
E05
72
hr
1657 5077 5505 0.9221 0.8886