LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XMD11-50 | 3.33 | uM | LJP6 | 3 | P08 | 72 | hr | 1235 | 1720 | 4156 | 0.4138 | 0.1659 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 1 | P02 | 72 | hr | 1235 | 2254 | 4156 | 0.5423 | 0.3488 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 2 | P02 | 72 | hr | 1235 | 2295 | 4156 | 0.5522 | 0.3628 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 3 | P02 | 72 | hr | 1235 | 2204 | 4156 | 0.5303 | 0.3316 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 1 | N08 | 72 | hr | 1235 | 2231 | 4156 | 0.5368 | 0.3409 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 2 | N08 | 72 | hr | 1235 | 2212 | 4156 | 0.5322 | 0.3344 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 3 | N08 | 72 | hr | 1235 | 2425 | 4156 | 0.5835 | 0.4073 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 1 | M14 | 72 | hr | 1235 | 1362 | 4156 | 0.3277 | 0.0434 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 2 | M14 | 72 | hr | 1235 | 1231 | 4156 | 0.2962 | -0.0015 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 3 | M14 | 72 | hr | 1235 | 1218 | 4156 | 0.2931 | -0.0060 |
| MCF7 | Afatinib | 10.0 | uM | LJP6 | 1 | G19 | 72 | hr | 1235 | 618 | 4156 | 0.1487 | -0.2114 |
| MCF7 | Afatinib | 10.0 | uM | LJP6 | 2 | G19 | 72 | hr | 1235 | 738 | 4156 | 0.1776 | -0.1703 |
| MCF7 | Afatinib | 10.0 | uM | LJP6 | 3 | G19 | 72 | hr | 1235 | 637 | 4156 | 0.1533 | -0.2049 |
| MCF7 | Sigma A6730 | 10.0 | uM | LJP5 | 1 | B19 | 72 | hr | 1235 | 1201 | 4156 | 0.2890 | -0.0118 |
| MCF7 | Sigma A6730 | 10.0 | uM | LJP5 | 2 | B19 | 72 | hr | 1235 | 1333 | 4156 | 0.3207 | 0.0334 |
| MCF7 | Sigma A6730 | 10.0 | uM | LJP5 | 3 | B19 | 72 | hr | 1235 | 1099 | 4156 | 0.2644 | -0.0467 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 1 | A13 | 72 | hr | 1235 | 329 | 4156 | 0.0792 | -0.3103 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 2 | A13 | 72 | hr | 1235 | 578 | 4156 | 0.1391 | -0.2251 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 3 | A13 | 72 | hr | 1235 | 630 | 4156 | 0.1516 | -0.2073 |
| MCF7 | AT-7519 | 10.0 | uM | LJP6 | 1 | K01 | 72 | hr | 1235 | 625 | 4156 | 0.1504 | -0.2090 |
| MCF7 | AT-7519 | 10.0 | uM | LJP6 | 2 | K01 | 72 | hr | 1235 | 796 | 4156 | 0.1915 | -0.1504 |
| MCF7 | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 1235 | 785 | 4156 | 0.1889 | -0.1542 |
| MCF7 | AZD 5438 | 10.0 | uM | LJP6 | 1 | J01 | 72 | hr | 1235 | 380 | 4156 | 0.0914 | -0.2929 |
| MCF7 | AZD 5438 | 10.0 | uM | LJP6 | 2 | J01 | 72 | hr | 1235 | 319 | 4156 | 0.0768 | -0.3138 |
| MCF7 | AZD 5438 | 10.0 | uM | LJP6 | 3 | J01 | 72 | hr | 1235 | 444 | 4156 | 0.1068 | -0.2710 |