LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 1 | M08 | 72 | hr | 1235 | 2698 | 4156 | 0.6492 | 0.5008 |
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 2 | M08 | 72 | hr | 1235 | 2652 | 4156 | 0.6381 | 0.4850 |
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 3 | M08 | 72 | hr | 1235 | 3115 | 4156 | 0.7495 | 0.6435 |
| MCF7 | Sirolimus | 3.33 | uM | LJP6 | 1 | L14 | 72 | hr | 1235 | 2444 | 4156 | 0.5880 | 0.4138 |
| MCF7 | Sirolimus | 3.33 | uM | LJP6 | 2 | L14 | 72 | hr | 1235 | 2550 | 4156 | 0.6136 | 0.4501 |
| MCF7 | Sirolimus | 3.33 | uM | LJP6 | 3 | L14 | 72 | hr | 1235 | 2604 | 4156 | 0.6265 | 0.4686 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 1235 | 3658 | 4156 | 0.8801 | 0.8294 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 2 | B08 | 72 | hr | 1235 | 3388 | 4156 | 0.8152 | 0.7370 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 3 | B08 | 72 | hr | 1235 | 3293 | 4156 | 0.7923 | 0.7045 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 1 | J08 | 72 | hr | 1235 | 2708 | 4156 | 0.6516 | 0.5042 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 2 | J08 | 72 | hr | 1235 | 3400 | 4156 | 0.8181 | 0.7411 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 3 | J08 | 72 | hr | 1235 | 3328 | 4156 | 0.8007 | 0.7165 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 1 | L02 | 72 | hr | 1235 | 1210 | 4156 | 0.2911 | -0.0087 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 2 | L02 | 72 | hr | 1235 | 1316 | 4156 | 0.3166 | 0.0276 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 3 | L02 | 72 | hr | 1235 | 1152 | 4156 | 0.2772 | -0.0285 |
| MCF7 | TGX221 | 3.33 | uM | LJP5 | 1 | H20 | 72 | hr | 1235 | 3018 | 4156 | 0.7262 | 0.6103 |
| MCF7 | TGX221 | 3.33 | uM | LJP5 | 2 | H20 | 72 | hr | 1235 | 3467 | 4156 | 0.8342 | 0.7641 |
| MCF7 | TGX221 | 3.33 | uM | LJP5 | 3 | H20 | 72 | hr | 1235 | 3196 | 4156 | 0.7690 | 0.6713 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 1 | O14 | 72 | hr | 1235 | 1090 | 4156 | 0.2623 | -0.0498 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 2 | O14 | 72 | hr | 1235 | 1168 | 4156 | 0.2810 | -0.0231 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 3 | O14 | 72 | hr | 1235 | 1034 | 4156 | 0.2488 | -0.0689 |
| MCF7 | Torin2 | 3.33 | uM | LJP5 | 1 | I20 | 72 | hr | 1235 | 1090 | 4156 | 0.2623 | -0.0498 |
| MCF7 | Torin2 | 3.33 | uM | LJP5 | 2 | I20 | 72 | hr | 1235 | 1146 | 4156 | 0.2757 | -0.0306 |
| MCF7 | Torin2 | 3.33 | uM | LJP5 | 3 | I20 | 72 | hr | 1235 | 1223 | 4156 | 0.2943 | -0.0042 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 1 | B14 | 72 | hr | 1235 | 1519 | 4156 | 0.3655 | 0.0971 |