Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Tofacitinib 0.3
uM
 2
CTACK
 15.0 61
N2645 2
CTACK
 16.0 45
RA2708 Tofacitinib 0.3
uM
 2
CTACK
 16.0 49
RA2708 2
CTACK
 15.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
CTACK
 15.0 62
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
CTACK
 16.5 70
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
CTACK
 16.0 66
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
CTACK
 15.5 58
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
CTACK
 14.0 57
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
CTACK
 14.5 60
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
CTACK
 14.0 46
RA2159 TNF-a 100
ng/mL
 2
CTACK
 16.5 54
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
CTACK
 14.0 53
N2645 TNF-a 100
ng/mL
 2
CTACK
 13.0 47
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
CTACK
 17.0 25
RA2708 TNF-a 100
ng/mL
 2
CTACK
 18.0 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 32.0 45
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 24.0 59
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 31.0 53
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 25.0 62
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 32.5 58
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 26.0 39
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 27.0 44
RA2159 IL-1 alpha 100
ng/mL
 2
CTACK
 30.0 55
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
CTACK
 29.0 46