Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 42.5 78
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 42.5 54
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 40.0 80
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 44.5 70
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 43.0 62
RA2159 IL-1 alpha 100
ng/mL
 4
MIF
 44.0 51
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 46.0 53
N2645 IL-1 alpha 100
ng/mL
 4
MIF
 47.0 69
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIF
 38.5 58
RA2708 IL-1 alpha 100
ng/mL
 4
MIF
 40.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIF
 255.5 62
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIF
 53.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIF
 34.0 69
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIF
 43.0 74
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIF
 230.0 61
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIF
 59.0 65
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIF
 31.0 50
RA2159 TNF-a 100
ng/mL
 4
MIF
 33.5 60
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIF
 31.5 62
N2645 TNF-a 100
ng/mL
 4
MIF
 34.0 52
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIF
 30.0 56
RA2708 TNF-a 100
ng/mL
 4
MIF
 29.5 52
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MIF
 35.5 34
RA2159 IKK16 2.0
uM
 4
MIF
 35.0 55
N2645 5z-7-oxozeaenol 0.6
uM
 4
MIF
 29.0 63