Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 23.5 64
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 27.0 57
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 29.0 51
RA1869 Poly(I:C) 2
ug/mL
 3
MIF
 35.0 52
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 28.5 44
N2759 Poly(I:C) 2
ug/mL
 3
MIF
 25.0 56
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 30.0 48
RA1931 Poly(I:C) 2
ug/mL
 3
MIF
 27.0 50
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 27.0 42
N2586 Poly(I:C) 2
ug/mL
 3
MIF
 28.0 49
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 46.0 51
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 47.5 62
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 35.0 56
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 35.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.0 60
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 38.0 53
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 34.0 57
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.0 62
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.5 44
RA1869 IL-1 alpha 100
ng/mL
 3
MIF
 46.5 54
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 35.0 41
N2759 IL-1 alpha 100
ng/mL
 3
MIF
 30.0 65
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 46.0 53
RA1931 IL-1 alpha 100
ng/mL
 3
MIF
 39.5 58
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 35.5 62