Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
TNFb
95.5 46
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
TNFb
100.5 62
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
TNFb
117.0 77
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
TNFb
112.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
TNFb
97.5 46
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
TNFb
106.0 45
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
TNFb
103.0 43
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
TNFb
95.5 58
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
TNFb
100.0 39
RA1869 IL-1 alpha 100
ng/mL
1
TNFb
108.0 39
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
TNFb
101.0 59
N2759 IL-1 alpha 100
ng/mL
1
TNFb
93.0 62
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
TNFb
113.0 52
RA1931 IL-1 alpha 100
ng/mL
1
TNFb
97.0 55
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
TNFb
109.5 38
N2586 IL-1 alpha 100
ng/mL
1
TNFb
79.5 22
RA1869 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
TNFb
37.5 38
RA1869 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
TNFb
34.5 46
N2759 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
TNFb
39.0 60
N2759 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
TNFb
33.0 45
RA1931 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
TNFb
32.0 45
RA1931 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
TNFb
33.5 46
N2586 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
TNFb
34.0 48
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
TNFb
35.0 53
RA1869 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
1
TNFb
37.0 59