Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 3
IL-17
35.5 58
RA1869 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-17
34.0 63
RA1869 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
39.0 69
N2759 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-17
40.5 58
N2759 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
36.0 66
RA1931 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-17
38.5 54
RA1931 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
43.0 67
N2586 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-17
35.0 68
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
39.0 74
RA1869 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
52.5 80
RA1869 Poly(I:C) 2
ug/mL
3
IL-17
72.0 57
N2759 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
60.0 58
N2759 Poly(I:C) 2
ug/mL
3
IL-17
63.5 74
RA1931 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
65.0 77
RA1931 Poly(I:C) 2
ug/mL
3
IL-17
75.0 50
N2586 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
74.0 72
N2586 Poly(I:C) 2
ug/mL
3
IL-17
65.0 61
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-17
34.0 68
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-17
43.0 81
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-17
37.0 68
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-17
38.0 58
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-17
33.5 68
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-17
39.0 54
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-17
34.5 70
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-17
38.0 77