Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-15
 491.5 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-15
 660.0 66
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-15
 1175.0 59
RA1869 TNF-a 100
ng/mL
 3
IL-15
 1473.0 54
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-15
 1011.0 51
N2759 TNF-a 100
ng/mL
 3
IL-15
 1257.0 49
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-15
 1052.0 68
RA1931 TNF-a 100
ng/mL
 3
IL-15
 1111.0 42
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-15
 1105.0 52
N2586 TNF-a 100
ng/mL
 3
IL-15
 1249.5 70
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-15
 342.0 50
RA1869 IKK16 2.0
uM
 3
IL-15
 363.5 52
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-15
 360.0 81
N2759 IKK16 2.0
uM
 3
IL-15
 344.0 75
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-15
 360.0 65
RA1931 IKK16 2.0
uM
 3
IL-15
 373.5 56
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-15
 332.0 71
N2586 IKK16 2.0
uM
 3
IL-15
 349.5 62
RA1869 Tofacitinib 0.3
uM
 3
IL-15
 394.0 63
RA1869 3
IL-15
 431.5 52
N2759 Tofacitinib 0.3
uM
 3
IL-15
 399.0 67
N2759 3
IL-15
 398.0 55
RA1931 Tofacitinib 0.3
uM
 3
IL-15
 342.0 61
RA1931 3
IL-15
 369.0 65
N2586 Tofacitinib 0.3
uM
 3
IL-15
 327.0 74