Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNF-a
 24.0 72
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
TNF-a
 24.0 73
RA2159 Sigma A6730 3.0
uM
 3
TNF-a
 16.0 84
N2586 IL-6 100
ug/mL
 3
TNF-a
 20.0 90
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
TNF-a
 22.0 77
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
TNF-a
 17.0 86
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNF-a
 18.0 71
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNF-a
 21.0 64
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
TNF-a
 19.0 74
N2586 Sigma A6730 3.0
uM
 3
TNF-a
 19.0 87
RA2159 IL-1 alpha 100
ng/mL
 3
TNF-a
 40.5 66
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 31.0 79
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 24.5 74
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 38.0 85
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 39.0 67
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 19.5 74
RA2159 PI103 0.1
uM
 3
TNF-a
 16.5 56
N2586 IL-1 alpha 100
ng/mL
 3
TNF-a
 46.0 78
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 34.5 72
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 36.0 68
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 38.0 55
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 18.5 54
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 33.0 91
N2586 PI103 0.1
uM
 3
TNF-a
 17.0 93
0
TNF-a
 14.0 74